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The Gene Ontology resource: enriching a GOld mine.

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اقرأ أكثر حفظ في قائمتي
  • المؤلفون: Gene Ontology Consortium; Gene Ontology Consortium
  • المصدر:
    Nucleic acids research; vol 49, iss D1, D325-D334; 0305-1048
  • نوع التسجيلة:
    Electronic Resource
  • الدخول الالكتروني :
    https://escholarship.org/uc/item/701467hb
    https://escholarship.org/
  • معلومة اضافية
    • Publisher Information:
      eScholarship, University of California 2021-01-01
    • نبذة مختصرة :
      The Gene Ontology Consortium (GOC) provides the most comprehensive resource currently available for computable knowledge regarding the functions of genes and gene products. Here, we report the advances of the consortium over the past two years. The new GO-CAM annotation framework was notably improved, and we formalized the model with a computational schema to check and validate the rapidly increasing repository of 2838 GO-CAMs. In addition, we describe the impacts of several collaborations to refine GO and report a 10% increase in the number of GO annotations, a 25% increase in annotated gene products, and over 9,400 new scientific articles annotated. As the project matures, we continue our efforts to review older annotations in light of newer findings, and, to maintain consistency with other ontologies. As a result, 20 000 annotations derived from experimental data were reviewed, corresponding to 2.5% of experimental GO annotations. The website (http://geneontology.org) was redesigned for quick access to documentation, downloads and tools. To maintain an accurate resource and support traceability and reproducibility, we have made available a historical archive covering the past 15 years of GO data with a consistent format and file structure for both the ontology and annotations.
    • الموضوع:
      Gene Ontology Consortium; Animals; Zebrafish; Humans; Mice; Rats; Drosophila melanogaster; Caenorhabditis elegans; Dictyostelium; Escherichia coli; Saccharomyces cerevisiae; Schizosaccharomyces; Arabidopsis; Internet; User-Computer Interface; Molecular Sequence Annotation; Gene Ontology; Genetics; 2.6 Resources and infrastructure (aetiology); Aetiology; Environmental Sciences; Biological Sciences; Information and Computing Sciences; Developmental Biology; article
    • Note:
      application/pdf
      Nucleic acids research vol 49, iss D1, D325-D334 0305-1048
    • Other Numbers:
      CDLER oai:escholarship.org:ark:/13030/qt701467hb
      qt701467hb
      https://escholarship.org/uc/item/701467hb
      https://escholarship.org/
      1367447698
    • Contributing Source:
      UC MASS DIGITIZATION
      From OAIster®, provided by the OCLC Cooperative.
    • الرقم المعرف:
      edsoai.on1367447698
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