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Increasing HIV-1 pretreatment drug resistance among antiretroviral-naive adults initiating treatment between 2006 and 2014 in Nairobi, Kenya
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- المؤلفون: Chung, Michael H.; Silverman, Rachel A.; Beck, Ingrid A.; Yatich, Nelly; Dross, Sandra; McKernan-Mullin, Jennifer; Bii, Stephen; Tapia, Kenneth; Stern, Joshua A.; Chohan, Bhavna; Sakr, Samah R.; Kiarie, James N.; Frenkel, Lisa M.
- نوع التسجيلة:
Electronic Resource
- الوصف المادي :
Pages 1680-1682
4 page(s)
- الدخول الالكتروني :
http://hdl.handle.net/10919/107613
- معلومة اضافية
- Publisher Information:
Lippincott Williams & Wilkins 2016-06-19
- نبذة مختصرة :
Antiretroviral-naïve adults initiating antiretroviral therapy in Nairobi, Kenya were tested for HIV-1 drug resistance at codons K103N, Y181C, G190A, M184V, and K65R using an oligonucleotide ligation assay. Prevalence of pretreatment drug resistance increased from 3.89% in 2006 to 10.93% in 2014 (P < 0.001), and 95% of those with resistance had at least one nonnucleoside reverse transcriptase inhibitor mutation. Resistance to tenofovir (K65R) was found in 2014 but not in 2006.
- الموضوع:
- الرقم المعرف:
10.1097.QAD.0000000000001110
- Note:
English
- Other Numbers:
VPI oai:vtechworks.lib.vt.edu:10919/107613
doi:10.1097/QAD.0000000000001110
EISSN:1473-5571
ISSN:0269-9370
1310159648
- Contributing Source:
VIRGINIA TECH
From OAIster®, provided by the OCLC Cooperative.
- الرقم المعرف:
edsoai.on1310159648
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