Cerebral aspergillosis in a liver transplant recipient: a case report of long-term survival after combined treatment with liposomal amphotericin B and surgery

Elsevier B.V. 1998

Cerebral aspergillosis is a life-threatening complication in liver transplant recipients, with mortality rates approaching 100%; treatment with amphotericin B is of limited efficacy because of its poor distribution in the cerebrospinal fluid and its systemic side effects. We report the case of a liver transplant recipient who developed recurrent cerebral Aspergillus fumigatus infection, and was successfully treated by combined surgical excision of the lesion and administration of liposomal amphotericin B. This first report of long-term complication-free survival in a liver transplant recipient suggests that therapy with liposomal amphotericin B may reduce the risk of recurrence of cerebral aspergillosis in these immunocompromised patients

cerebral aspergillosi; liposomal amphotericin B; liver transplantation; MED/12 - GASTROENTEROLOGIA; info:eu-repo/semantics/article

Open access content. Open access content

English

ITBAO oai:boa.unimib.it:10281/1302
10.1016/S0168-8278(98)80329-2
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-0032032422
1308890707

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