A review: Radiographic iodinated contrast media-induced thyroid dysfunction.

eScholarship, University of California 2015-02-01

ContextThyroid hormone production is dependent on adequate iodine intake. Excess iodine is generally well-tolerated, but thyroid dysfunction can occur in susceptible individuals after excess iodine exposure. Radiological iodinated contrast media represent an increasingly common source of excess iodine.ObjectiveThis review will discuss the thyroidal response after acute exposure to excess iodine; contrast iodine-induced thyroid dysfunction; risks of iodine-induced thyroid dysfunction in vulnerable populations, such as the fetus, neonate, and patients with impaired renal function; and recommendations for the assessment and treatment of contrast iodine-induced thyroid dysfunction.MethodsData for this review were identified by searching PubMed, Google Scholar, and references from relevant articles from 1948 to 2014.ConclusionsWith the increase in the use of computed tomography scans in the United States, there is increasing risk of contrast-induced thyroid dysfunction. Patients at risk of developing iodine-induced thyroid dysfunction should be closely monitored after receiving iodinated contrast media and should be treated as needed.

Humans; Thyroid Diseases; Contrast Media; Thyroid Function Tests; Prevention; Endocrinology & Metabolism; Clinical Sciences; Paediatrics and Reproductive Medicine; article

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The Journal of clinical endocrinology and metabolism vol 100, iss 2, 376-383 0021-972X

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