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Genetic analysis of muscle development in Drosophila melanogaster

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  • معلومة اضافية
    • Publisher Information:
      Academic Press 1989
    • نبذة مختصرة :
      The different thoracic muscles of Drosophila are affected specifically in the mutants: stripe (sr), erect wing (ewg), vertical wings (vtw), and nonjumper (nj). We have tested the extent of this specificity by means of a genetic analysis of these loci, multiple mutant combinations, and gene dosage experiments. A quantitative, rather than a qualitative, specificity is found in the mutant phenotypes. All muscles are altered by mutations in any given gene, but the severity of these alterations is muscle specific. The locus stripe seems to have a polar organization where different allelic combinations show quantitative specificity in the muscle affected. In addition to the muscle phenotypes, neural alterations are detected in these mutants. The synergism found between ewg, vtw and ewg, sr as well as the dosage effect of the distal end of the X chromosome upon the expression of ewg and sr suggests the existence of functional relationships among the loci analyzed.
    • الموضوع:
      artículo
    • Availability:
      Open access content. Open access content
      openAccess
    • Note:
      English
    • Other Numbers:
      CTK oai:digital.csic.es:10261/72771
      Developmental Biology 131: 439- 454 (1989)
      0012-1606
      10.1016/S0012-1606(89)80016-8
      1103404022
    • Contributing Source:
      CSIC
      From OAIster®, provided by the OCLC Cooperative.
    • الرقم المعرف:
      edsoai.on1103404022
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