MLN8054, a small molecule inhibitor of aurora kinase a, sensitizes androgen-resistant prostate cancer to radiation.

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المؤلفون: Moretti, Luigi; Niermann, Kenneth; Schleicher, Stephen; Giacalone, Nicholas J; Varki, Vinod; Kim, Kwang Woon; Kopsombut, Prapaporn; Jung, Dae Kwang; Lu, Bo
المصدر:
International journal of radiation oncology, biology, physics, 80 (4
نوع التسجيلة:
Electronic Resource
الدخول الالكتروني :
https://dipot.ulb.ac.be/dspace/bitstream/2013/125887/1/Elsevier_107414.pdf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/125887
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL

معلومة اضافية
- Publisher Information:
  2011-07
- نبذة مختصرة :
  To determine whether MLN8054, an Aurora kinase A (Aurora-A) inhibitor causes radiosensitization in androgen-insensitive prostate cancer cells in vitro and in vivo.
  Journal Article
  Research Support, U.S. Gov't, Non-P.H.S.
  SCOPUS: ar.j
  info:eu-repo/semantics/published
- الموضوع:
  Cancérologie; Androgens -- therapeutic use; Animals; Apoptosis -- radiation effects; Benzazepines -- therapeutic use; Caspase 3 -- analysis; Cell Cycle; Cell Line, Tumor; Cell Survival -- drug effects -- radiation effects; DNA Breaks, Double-Stranded; Drug Resistance, Neoplasm -- drug effects; Histones -- analysis; Humans; Immunoblotting -- methods; Ki-67 Antigen -- analysis; Male; Mice; Mice, Nude; Nocodazole -- therapeutic use; Prostatic Neoplasms -- drug therapy -- pathology -- radiotherapy; Protein-Serine-Threonine Kinases -- antagonists & inhibitors; Radiation Tolerance -- drug effects; Radiation-Sensitizing Agents -- therapeutic use; Aurora kinase A; MLN8054; Prostate cancer; Radiation; info:eu-repo/semantics/article; info:ulb-repo/semantics/articlePeerReview; info:ulb-repo/semantics/openurl/article
- Availability:
  Open access content. Open access content
  1 full-text file(s): info:eu-repo/semantics/restrictedAccess
- Note:
  1 full-text file(s): application/pdf
  English
- Other Numbers:
  EQY oai:dipot.ulb.ac.be:2013/125887
  uri/info:doi/10.1016/j.ijrobp.2011.01.060
  uri/info:pii/S0360-3016(11)00235-5
  uri/info:pmid/21514073
  uri/info:scp/79959355129
  812601253
- Contributing Source:
  UNIVERSITE LIBRE DE BRUXELLES
  From OAIster®, provided by the OCLC Cooperative.
- الرقم المعرف:
  edsoai.ocn812601253

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MLN8054, a small molecule inhibitor of aurora kinase a, sensitizes androgen-resistant prostate cancer to radiation.

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