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Progressive multifocal leukoencephalopathy developing in a fludarabine naïve patient with chronic lymphocytic leukemia

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  • المؤلفون: Ooi,Melissa; Kelly,Peter J; Farrell,Michael; Murphy,Philip; O’Gorman,Peter
  • نوع التسجيلة:
    Electronic Resource
  • الدخول الالكتروني :
    https://www.dovepress.com/progressive-multifocal-leukoencephalopathy-developing-in-a-fludarabine-peer-reviewed-fulltext-article-IJGM
    info:eu-repo/semantics/altIdentifier/doi/10.2147/IJGM.S4380
  • معلومة اضافية
    • Publisher Information:
      Dove Press 2009-01-12
    • نبذة مختصرة :
      Melissa G Ooi1, Peter J Kelly2, Michael Farrell3, Philip Murphy4, Peter O’Gorman11Department of Hematology; 2Department of Neurology, Mater Misericordiae Hospital, Dublin, Ireland; 3Department of Neuropathology; 4Department of Hematology, Beaumont Hospital, Dublin, IrelandAbstract: We report a case of progressive multifocal leukoencephalopathy developing in a fludarabine-naïve patient with chronic lymphocytic leukemia. We suggest that progressive multifocal leukoencephalopathy should be considered in any chronic lymphocytic leukemia patient with unexplained neurological symptoms. Treatment history does not necessarily require fludarabine. Intrathecal cytosine arabinoside although unsuccessful in this patient, is a therapeutic option to consider in patients experiencing side effects from systemic therapy.Keywords: progressive multifocal leukoencephalopathy, chronic lymphocytic leukemia, JC virus, fludarabine, intrathecal cytosine arabinoside
    • الموضوع:
    • Availability:
      Open access content. Open access content
      info:eu-repo/semantics/openAccess
    • Note:
      text/html
      English
    • Other Numbers:
      NZDMP oai:dovepress.com/2787
      727292347
    • Contributing Source:
      DOVE MEDL PRESS LTD
      From OAIster®, provided by the OCLC Cooperative.
    • الرقم المعرف:
      edsoai.ocn727292347
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