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FAM21 directs SNX27–retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus

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  • معلومة اضافية
    • بيانات النشر:
      Nature Portfolio, 2016.
    • الموضوع:
      2016
    • Collection:
      LCC:Science
    • نبذة مختصرة :
      Endosomes maintain cellular homeostasis by sorting, recycling and degrading endocytosed cargoes. Here the authors show that the SNX27-retromer-WASH complex acts as a hub to direct cargoes to the plasma membrane by blocking their transport to lysosomes and Golgi apparatus.
    • File Description:
      electronic resource
    • ISSN:
      2041-1723
    • Relation:
      https://doaj.org/toc/2041-1723
    • الرقم المعرف:
      10.1038/ncomms10939
    • الرقم المعرف:
      edsdoj.92b21014b193476cac6a065734c84f81