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Single cell analysis of kynurenine and System L amino acid transport in T cells

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  • معلومة اضافية
    • بيانات النشر:
      Nature Portfolio, 2018.
    • الموضوع:
      2018
    • Collection:
      LCC:Science
    • نبذة مختصرة :
      Kynurenine is an immunomodulatory aryl hydrocarbon receptor (AHR) ligand. Here the authors show, using a new flow cytometry based method, that kynurenine needs to be transported across the plasma membrane of activated T cells by the transporter protein SLC7A5 to activate the AHR.
    • File Description:
      electronic resource
    • ISSN:
      2041-1723
    • Relation:
      https://doaj.org/toc/2041-1723
    • الرقم المعرف:
      10.1038/s41467-018-04366-7
    • الرقم المعرف:
      edsdoj.860c1c2a7b44c229d50bae26faa0f86