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The Risk Threshold for Hemoglobin A1c Associated With Albuminuria: A Population-Based Study in China

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اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • بيانات النشر:
      Frontiers Media S.A., 2021.
    • الموضوع:
      2021
    • Collection:
      LCC:Diseases of the endocrine glands. Clinical endocrinology
    • نبذة مختصرة :
      BackgroundDiabetic kidney disease (DKD) is a kind of common microvascular complication of diabetes. This study aims to explore the possible links between blood sugar level and albuminuria, providing the exact cut point of the “risk threshold” for blood glucose with DKD.MethodsThe relationship between blood glucose and albuminuria was modeled using linear and logistic regression in the REACTION study cohorts (N= 8932). Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated by logistic regression model. Two-slope linear regression was used to simulate associations between blood glucose and ACR.ResultsWe found that the increase in ACR was accompanied by increased HbA1c, with a turning point at 5.5%. The positive correlation remained highly significant (P
    • File Description:
      electronic resource
    • ISSN:
      1664-2392
    • Relation:
      https://www.frontiersin.org/articles/10.3389/fendo.2021.673976/full; https://doaj.org/toc/1664-2392
    • الرقم المعرف:
      10.3389/fendo.2021.673976
    • الرقم المعرف:
      edsdoj.7b2a31564a24430d9593259b7dd2f2ca