Intervention efficacy of cognitive behavioral therapy on prolonged grief disorder： a Meta-analysis

BackgroundProlonged grief disorder （PGD） has serious impact on the quality of patients' work and life. Previous relevant studies have explored the intervention effect of cognitive behavioral therapy（CBT） on PGD， but their conclusions remain controversial due to differences in frequency， time and content of intervention.ObjectiveTo explore the intervention effects of CBT on the PGD through Meta-analysis， so as to provide references for clinical treatment.MethodsOn October 22， 2022， the database of VIP， China Biomedical Literature Database， Wanfang， CNKI， Embase， Cochrane Library， PubMed and Web of Science were searched systematically， and randomized controlled trials （RCTs） of CBT in treating PGD was collected. Outcome indicators include sadness， depression， anxiety and somatization symptoms. RevMan 5.3 was used for Meta-analysis.ResultsA total of 7 articles were included with a total sample size of 528 cases. Meta-analysis results showed that the study group had lower scores than the control group for grief （SMD=-0.78，95% CI：-1.27~-0.29）， depression （SMD=-0.45，95% CI：-0.73~-0.17） and anxiety symptom （SMD=-0.38，95% CI：-0.59~-0.18） with statistically significant differences. However， the difference of scores for somatization symptom between two groups was not significant （SMD=-0.01，95% CI：-0.26~0.25）.ConclusionCBT may contribute to improving the symptoms of grief， depression and anxiety in PGD patients but unsatisfactory efficacy on somatization symptom.