نبذة مختصرة : Background: Post-Dural Puncture Headache (PDPH) is a common problem that happens after the Dura-arachnoid puncture during the procedure for diagnosis, therapy, and spinal anesthesia administration. This study aimed to assess the magnitude and associated factors of post-dural puncture headache (PDPH) after spinal anesthesia in surgical patients. Method: A multi-center institution-based cross-sectional study was conducted from September 1 to November 30, 2021, on 402 patients who came for an operation under spinal anesthesia. Data was entered and analyzed using Statistical Package for Social Sciences (SPSS) window version 26. Data were collected using a structured questionnaire. Descriptive statistics were expressed in percentages and presented with tables and figures. Both Bivariable and multivariable logistic analyses were done to identify the magnitude and associated factors of post-Dural puncture headache (PDPH) after spinal anesthesia in surgical patients. P
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