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Novel Cadmium Telluride Quantum Dot (QD) Fluorescent Probe for the Sensitive Determination of the Hepatocellular Carcinoma (HCC) Biomarker Alpha-Fetoprotein (AFP) ...

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اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • بيانات النشر:
      Taylor & Francis
    • الموضوع:
      2024
    • Collection:
      DataCite Metadata Store (German National Library of Science and Technology)
    • نبذة مختصرة :
      The concentration of alpha-fetoprotein (AFP) generally increases in the serum of hepatocellular carcinoma (HCC) patients. Hence, AFP is a biomarker for HCC detection, diagnosis, and treatment. However, the sensitivity is unsatisfactory. Here a fluorescent probe based on CdTe quantum dots (QDs-AFP Ab ) was prepared and a simple sensitive fluorescence immunoassay on nitrocellulose membranes (NFIA) was developed for alpha-fetoprotein. This method exhibited a low detection limit of 2.18 pg/mL with a linear range from 10 to 1.0 × 10 7 pg/mL. In addition, the sensitivity allowed the identification of HCC and non-HCC serum. This method is sensitive, easy, and low-cost for the diagnosis of HCC. ...
    • Relation:
      https://dx.doi.org/10.6084/m9.figshare.26049811; https://dx.doi.org/10.1080/00032719.2024.2367231
    • الرقم المعرف:
      10.6084/m9.figshare.26049811.v1
    • Rights:
      Creative Commons Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/legalcode ; cc-by-4.0
    • الرقم المعرف:
      edsbas.FD5D5A04