Chikungunya : atypical and severe disease manifestations

Atypical and severe manifestations ; • Although most chikungunya virus infections result in fever and arthralgia, other clinical manifestations can occur. ; • Atypical or severe clinical manifestations can be due to the direct effects of the virus, immunologic response to the virus, ; drug toxicity, or diseases unrelated to chikungunya virus infection. ; • Some atypical or severe manifestations are more common in certain groups. For example, vesiculobullous lesions, febrile ; seizures, and meningoencephalitis have been reported in infants and young children. ; • Since many atypical and severe clinical manifestations will be unrelated to chikungunya virus infection, healthcare ; providers should consider and evaluate for other etiologies. ; Atypical and severe manifestations -- Risk groups for severe disease -- Pregnant women and newborns -- Treatment and clinical management -- Selected references.