Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Analysis of OXA-204 carbapenemase-producing Enterobacteriaceae reveals possible endoscopy-associated transmission, France, 2012 to 2014

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • Contributors:
      Centre National de Référence de la Résistance aux Antibiotiques (CNR); Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon); Service de bactériologie Besançon; Université de Franche-Comté (UFC); Université Bourgogne Franche-Comté COMUE (UBFC); Hôpital Bicêtre AP-HP, Le Kremlin-Bicêtre; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP); Regional coordinating centre for nosocomial infection control (C-CLIN Paris Nord); CHU Pitié-Salpêtrière AP-HP; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU); Université de Lausanne = University of Lausanne (UNIL); Université de Fribourg = University of Fribourg (UNIFR)
    • بيانات النشر:
      HAL CCSD
      European Centre for Disease Prevention and Control
    • الموضوع:
      2017
    • Collection:
      Université de Franche-Comté (UFC): HAL
    • نبذة مختصرة :
      International audience ; OXA-48-like beta-lactamase producing bacteria are now endemic in several European and Mediterranean countries. Among this carbapenemase family, the OXA-48 and OXA-181 variants predominate, whereas other variants such as OXA-204 are rarely reported. Here, we report the molecular epidemiology of a collection of OXA-204-positive enterobacterial isolates (n = 29) recovered in France between October 2012 and May 2014. This study describes the first outbreak of OXA-204-producing Enterobacteriaceae in Europe, involving 12 isolates of an ST90 Escherichia coli clone and nine isolates of an ST147 Klebsiella pneumoniae clone. All isolates co-produced the cephalosporinase CMY-4, and 60% of them co-produced the extended-spectrum beta-lactamase CTX-M-15. The blaOXA-204 gene was located on a 150-kb IncA/C plasmid, isolated from various enterobacterial species in the same patient, indicating a high conjugative ability of this genetic vehicle.
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/29233256; hal-01690478; https://hal.science/hal-01690478; https://hal.science/hal-01690478/document; https://hal.science/hal-01690478/file/eurosurveillance.pdf; PUBMED: 29233256; PUBMEDCENTRAL: PMC5727592
    • الرقم المعرف:
      10.2807/1560-7917.ES.2017.22.49.17-00048
    • الدخول الالكتروني :
      https://hal.science/hal-01690478
      https://hal.science/hal-01690478/document
      https://hal.science/hal-01690478/file/eurosurveillance.pdf
      https://doi.org/10.2807/1560-7917.ES.2017.22.49.17-00048
    • Rights:
      info:eu-repo/semantics/OpenAccess
    • الرقم المعرف:
      edsbas.FBC50C9