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Incidence and Prevalence of Neovascular Age-Related Macular Degeneration in France between 2008 and 2018

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  • معلومة اضافية
    • Contributors:
      Service d'Ophtalmologie (CHU de Dijon); Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon); Centre des Sciences du Goût et de l'Alimentation Dijon (CSGA); Université de Bourgogne (UB)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Dijon; Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro); Hôpital Intercommunal Créteil; Hôpital Gui de Chauliac CHU Montpellier; Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier); Desgenettes Military Hospital; Centre d’imagerie et de laser; Centre d'investigation clinique Quinze-Vingts CHNO (CIC1423 - CIC QUINZE-VINGTS); Institut Hospitalo-Universitaire FOReSIGHT (IHU FOReSIGHT); Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (CHNO); Sorbonne Université (SU)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (CHNO); Sorbonne Université (SU)-Sorbonne Université (SU); IQVIA; Novartis Pharma S.A.S.; Bordeaux population health (BPH); Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM)
    • بيانات النشر:
      HAL CCSD
    • الموضوع:
      2022
    • Collection:
      Inserm: HAL (Institut national de la santé et de la recherche médicale)
    • نبذة مختصرة :
      International audience ; PURPOSE: This study aimed to estimate the incidence and prevalence of neovascular age-related macular degeneration (nAMD) in the French population between 2008 and 2018. DESIGN: This was a retrospective, longitudinal population study using health care consumption data from the Système National des Données de Santé (SNDS; the French National Health Information Database), which covers approximately 99% of the French population. PARTICIPANTS: We identified individuals treated for nAMD from the French population 50 years of age and older. Identification criteria were nAMD diagnosis or reimbursement of nAMD treatments (anti-vascular endothelial growth factor intravitreal injection or dynamic phototherapy with verteporfin). Exclusion criteria were high myopia, diagnosis of other retinal diseases, and other treatments for macular diseases (dexamethasone implant, laser therapy, etc.). METHODS: We calculated incidence and prevalence based on the age-matched general population in France. Adjustment for age and sex was also performed for incidence. MAIN OUTCOME MEASURES: Incidence and prevalence of nAMD in the French population between 2008 and 2018. RESULTS: Between 2008 and 2018, we identified 342 961 patients with nAMD (67.5% women). Mean ± standard deviation age at nAMD diagnosis or first treatment increased from 78.8 ± 8.1 years in 2008 to 81.2 ± 7.9 years in 2018. In 2018, annual incidence was 0.149% and prevalence was 1.062% for the French population 50 years of age or older. Incidence was stable over the 10-year period. Annual incidence increased with age (0.223%, 0.380%, and 0.603% in those 60 years of age or older, 70 years of age or older, and 80 years of age or older, respectively), with similar trends for prevalence. No major differences were observed among the 14 regions of France for incidence or prevalence. Neovascular age-related macular degeneration incidence in 2018 was not impacted by the availability of primary or ophthalmology care in patients' localities. CONCLUSIONS: The ...
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/3624646186; hal-03826470; https://hal.inrae.fr/hal-03826470; PUBMED: 3624646186; PUBMEDCENTRAL: PMC9562296; WOS: 001026422300004
    • الرقم المعرف:
      10.1016/j.xops.2022.100114
    • Rights:
      http://creativecommons.org/licenses/by-nc-nd/
    • الرقم المعرف:
      edsbas.EEBF1B5B