Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Long-distance endosome trafficking drives fungal effector production during plant infection

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
  • معلومة اضافية
    • الموضوع:
      2014
    • Collection:
      University of East Anglia: UEA Digital Repository
    • نبذة مختصرة :
      To cause plant disease, pathogenic fungi can secrete effector proteins into plant cells to suppress plant immunity and facilitate fungal infection. Most fungal pathogens infect plants using very long strand-like cells, called hyphae, that secrete effectors from their tips into host tissue. How fungi undergo long-distance cell signalling to regulate effector production during infection is not known. Here we show that long-distance retrograde motility of early endosomes (EEs) is necessary to trigger transcription of effector-encoding genes during plant infection by the pathogenic fungus Ustilago maydis. We demonstrate that motor-dependent retrograde EE motility is necessary for regulation of effector production and secretion during host cell invasion. We further show that retrograde signalling involves the mitogen-activated kinase Crk1 that travels on EEs and participates in control of effector production. Fungal pathogens therefore undergo long-range signalling to orchestrate host invasion.
    • File Description:
      application/pdf
    • Relation:
      https://ueaeprints.uea.ac.uk/id/eprint/77632/1/Published_Version.pdf; Bielska, Ewa, Higuchi, Yujiro, Schuster, Martin, Steinberg, Natascha, Kilaru, Sreedhar, Talbot, Nicholas J. and Steinberg, Gero (2014) Long-distance endosome trafficking drives fungal effector production during plant infection. Nature Communications, 5 (1). ISSN 2041-1723
    • الرقم المعرف:
      10.1038/ncomms6097
    • الدخول الالكتروني :
      https://ueaeprints.uea.ac.uk/id/eprint/77632/
      https://ueaeprints.uea.ac.uk/id/eprint/77632/1/Published_Version.pdf
      https://doi.org/10.1038/ncomms6097
    • Rights:
      cc_by
    • الرقم المعرف:
      edsbas.ED9A2D0