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A streamlined pathway for transcatheter aortic valve implantation: the BENCHMARK study

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  • معلومة اضافية
    • Contributors:
      University Medical Center of Schleswig–Holstein = Universitätsklinikum Schleswig-Holstein (UKSH); Christian-Albrechts-Universität zu Kiel = Christian-Albrechts University of Kiel = Université Christian-Albrechts de Kiel (CAU); Endothélium, valvulopathies et insuffisance cardiaque (EnVI); Université de Rouen Normandie (UNIROUEN); Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM); University of British Columbia Vancouver; Alma Mater Studiorum Università di Bologna = University of Bologna (UNIBO); Hospital Regional Universitario de Málaga = Regional University Hospital of Malaga Spain; University of Medicine and Pharmacy “Carol Davila” Bucharest (UMPCD); Centre Hospitalier Régional Universitaire de Tours (CHRU Tours); University Hospital of Montpellier; Centre Hospitalier Universitaire de Rennes CHU Rennes = Rennes University Hospital Ponchaillou; Laboratoire Traitement du Signal et de l'Image (LTSI); Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM); Hospital de la Santa Creu i Sant Pau; Institut Mutualiste de Montsouris (IMM); Institute for Clinical and Experimental Medicine (IKEM); Instituto de Investigación Sanitaria del Hospital Clínico San Carlos Madrid, Spain (IdISSC); University of Barcelona; Georg-August-University = Georg-August-Universität Göttingen; University of Heidelberg, Medical Faculty; CHU Pitié-Salpêtrière AP-HP; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU); James Cook University (JCU); None
    • بيانات النشر:
      HAL CCSD
      Oxford University Press (OUP)
    • الموضوع:
      2024
    • Collection:
      Université de Rennes 1: Publications scientifiques (HAL)
    • نبذة مختصرة :
      International audience ; BACKGROUND AND AIMS: There is significant potential to streamline the clinical pathway for patients undergoing transcatheter aortic valve implantation (TAVI). The purpose of this study was to evaluate the effect of implementing BENCHMARK best practices on the efficiency and safety of TAVI in 28 sites in 7 European countries. METHODS: This was a study of patients with severe symptomatic aortic stenosis (AS) undergoing TAVI with balloon-expandable valves before and after implementation of BENCHMARK best practices. Principal objectives were to reduce hospital length of stay (LoS) and duration of intensive care stay. Secondary objective was to document patient safety. RESULTS: Between January 2020 and March 2023, 897 patients were documented prior to and 1491 patients after the implementation of BENCHMARK practices. Patient characteristics were consistent with a known older TAVI population and only minor differences. Mean LoS was reduced from 7.7 ± 7.0 to 5.8 ± 5.6 days (median 6 vs. 4 days; P < .001). Duration of intensive care was reduced from 1.8 to 1.3 days (median 1.1 vs. 0.9 days; P < .001). Adoption of peri-procedure best practices led to increased use of local anaesthesia (96.1% vs. 84.3%; P < .001) and decreased procedure (median 47 vs. 60 min; P < .001) and intervention times (85 vs. 95 min; P < .001). Thirty-day patient safety did not appear to be compromised with no differences in all-cause mortality (0.6% in both groups combined), stroke/transient ischaemic attack (1.4%), life-threatening bleeding (1.3%), stage 2/3 acute kidney injury (0.7%), and valve-related readmission (1.2%). CONCLUSIONS: Broad implementation of BENCHMARK practices contributes to improving efficiency of TAVI pathway reducing LoS and costs without compromising patient safety.
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/38554125; hal-04534032; https://hal.science/hal-04534032; https://hal.science/hal-04534032/document; https://hal.science/hal-04534032/file/ehae147.pdf; PUBMED: 38554125
    • الرقم المعرف:
      10.1093/eurheartj/ehae147
    • Rights:
      http://creativecommons.org/licenses/by/ ; info:eu-repo/semantics/OpenAccess
    • الرقم المعرف:
      edsbas.E9ECCB70