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Hemodynamic determination of risk turbulent flow on atherosclerotic and endothelial shear stress in coronary lumen stenosis regimes ; Determinação hemodinâmica do risco de fluxo turbulento sobre o cisalhamento aterosclerótico e endotelial em regimes de estenose de lúmen coronariano

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  • معلومة اضافية
    • بيانات النشر:
      Universidade de São Paulo. Faculdade de Medicina
    • الموضوع:
      2023
    • Collection:
      Universidade de São Paulo: Portal de Revistas da USP
    • نبذة مختصرة :
      Introduction: Acute myocardial infarction is considered one of the main clinical conditions that cause death in the world. Its prevalence denotes its importance and several reasons can culminate in sudden obstruction of the coronary lumen. Objective: to determine the influence of shear stress for the early detection of atheromatous plaques at risk of rupture or erosion, making it possible to predict infarction in these situations. Methodology: articles were selected from the PubMed, Lilacs, Medline, Scielo and Google Scholar databases, using DeCS and MeSH descriptors to homogenize the results. As the discoveries in the field of study are recent, filters were not used for the research, linearly employing the articles mentioned above, to support this review. Results / discussion: The models brought from fluid mechanics associated with chemical/biological measurements of detection by laboratory and imaging tests have pointed to pathological shear stress as a stimulus for damage to atheromatous plaques and consequent exposure to the possibility of abrupt obstruction of coronary lumen. Conclusion: Many of the current essays have been pointing to this possible pillar of investigation, however, several variables involve the subject, still requiring a deepening in theoretical and practical studies to strengthen and map the details of this mechanical aspect, in relation to the consequent infarction. ; Introdução: O infarto agudo do miocárdio é considerado como uma das principais condições clínicas causadoras de mortes no mundo. Sua prevalência denota sua importância e diversos motivos podem culminar na obstrução repentina do lúmen coronariano. Objetivo: determinar a influência da tensão de cisalhamento para a detecção precoce de placas de ateroma sujeitas a riscos de ruptura ou erosão, tornando-se possível prever o infarto nestas situações. Metodologia: artigos foram selecionados nos bancos de dados PubMed, Lilacs, Medline, SciELO e Google Scholar, utilizando descritores DeCS e MeSH para homogeneizar os resultados. Por ...
    • File Description:
      application/pdf
    • Relation:
      https://www.revistas.usp.br/revistadc/article/view/202735/192358; https://www.revistas.usp.br/revistadc/article/view/202735/192357; https://www.revistas.usp.br/revistadc/article/view/202735
    • Rights:
      Copyright (c) 2023 Mario Henrique Quim Ferreira, Beatriz Cheregati Fumagalli, Ana Beatriz Teixeira, Aristeu da Silveira Neto, Leandro Kefalás Barbosa ; https://creativecommons.org/licenses/by-sa/4.0
    • الرقم المعرف:
      edsbas.E5C9B4BA