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Role of Growth Factors in the Adhesive Process in the Abdominal Cavity ; Роль факторов роста при спаечном процессе в брюшной полости

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  • معلومة اضافية
    • بيانات النشر:
      Scientific Centre for Family Health and Human Reproduction Problems
    • الموضوع:
      2019
    • Collection:
      Acta Biomedica Scientifica
    • نبذة مختصرة :
      Fibroproliferative diseases have been described in the lungs, kidneys, liver, eyes, heart, skin, and abdomen. Each fibrous pathology has causal factors and pathological manifestations characteristic of this organ and this condition. However, there are common mechanisms underlying many fibrous pathologies. This gives potential value to studies focused on specific processes, among which is the adhesive process in the abdominal cavity. The study of growth factors in the formation of connective tissue contributes to a better understanding of the pathogenetic picture in this pathology. It is shown that vascular endothelial growth factor, fibroblast growth factor, transforming growth factor, platelet growth factor, insulin-like growth factor and keratinocyte growth factor participate in the development of abdominal adhesions. Each of these factors contributes significantly to the formation of peritoneal fibrosis.Thus, damage to any tissue initiates a complex multistage process, which is regulated by a large number of cytokines and growth factors. Growth factors control cell migration, proliferation, differentiation, and survival. In addition, they are able to influence the expression of other factors involved in the regenerative response. Understanding the process that develops during the formation of the adhesive process in the abdominal cavity and the growth factors affecting it is important for their further use in order to prevent the pathological process. ; Факторы роста – высокоспециализированные биологически активные низкомолекулярные полипептиды, контролирующие процессы роста, развития и поддержания клеточных популяций. Систематический обзор посвящён роли различных факторов роста в развитии спаечного процесса в брюшной полости. Показано, что в развитии спаечного процесса в брюшной полости участвуют такие факторы роста, как ростовой фактор эндотелия сосудов, фактор роста фибробластов, трансформирующий фактор роста, тромбоцитарный фактор роста, инсулиноподобный ростовой фактор и фактор роста кератиноцитов. ...
    • File Description:
      application/pdf
    • Relation:
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    • الرقم المعرف:
      10.29413/ABS.2019-4.5.16
    • الدخول الالكتروني :
      https://www.actabiomedica.ru/jour/article/view/2177
      https://doi.org/10.29413/ABS.2019-4.5.16
    • Rights:
      Authors who publish with this journal agree to the following terms:Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access). ; Авторы, публикующие в данном журнале, соглашаются со следующим:Авторы сохраняют за собой авторские права на работу и предоставляют журналу право первой публикации работы на условиях лицензии Creative Commons Attribution License, которая позволяет другим распространять данную работу с обязательным сохранением ссылок на авторов оригинальной работы и оригинальную публикацию в этом журнале.Авторы сохраняют право заключать отдельные контрактные договорённости, касающиеся не-эксклюзивного распространения версии работы в опубликованном здесь виде (например, размещение ее в институтском хранилище, публикацию в книге), со ссылкой на ее оригинальную публикацию в этом журнале.Авторы имеют право размещать их работу в сети Интернет (например в институтском хранилище или персональном сайте) до и во время процесса рассмотрения ее данным журналом, так как это может привести к продуктивному обсуждению и большему количеству ссылок на данную работу (См. The Effect of Open Access).
    • الرقم المعرف:
      edsbas.E5623E4