نبذة مختصرة : Introduction: Several studies try to determine the evolution of SLE patients entering the ICU (intensive care unit), mortality and the probable factors associated with it. This research will contribute to better characterize this population. Material and Methods: Observational, retrospective,and transversal study. Inclusion criteria: both sexes, older than 15 years of age, diagnosis of SLE according to ACR criteria (American College Rheumatology), admitted in the Hospital de Clinicas-A ICU, from January 2009 to December 2013. Results: Of 31 patients with SLE , 90.3% were female with a mean age of 34.3 ± 15.2 years. Average tiem of SLE diagnosis before admission to the ICU was 36.2 ± 56.4 months. The mean SLE DAI was 17.8 ± 10.4 points. The duration of hospital stay prior to entry into the ICU was 10.6 ± 7.7 days). The most frequent causes of admission were medical (87.1%). 80% of patients due to infection, out of which 80% were nosocomial infections, mainly pulmonary (72%). Only 6 were admitted for lupus activity without (19.4%) obvious infection. At admission the mean value of APACHE II was 21.6 ± 8.1. 25 patients required mechanical ventilation, with a duration of 8.4 ± 10.5 days. The time spent in the ICU was 8.5 ± 10.2 days. 15 patients had multiple organ failure (48.4%). Out of all the patients admitted to the ICU, 14 (45.2% died). Regarding the analysis of risk factors for mortality the following were identified: APACHE II above 15 points (p = 0.007), albumin < 2 (p = 0.04), need for ARM (p = 0.01), PaFiO2 to IUC entrance 8 points showed a mortality trend (p = 0.07). Conclusions: The most frequent cause of admission was respiratory failure,due to pneumonia, requiring ARM. Factors associated with mortality: APACHE II> 20, severe hypoalbuminemia, need for ARM, PaFiO2 ; Introducción: Varios estudios tratan de determinar la evolución de pacientes con LES que ingresan a UCIA, su mortalidad y los probables factores asociados a la misma. Esta investigación servirá para caracterizar mejor a esta población. ...
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