Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Multisystem inflammatory syndrome (MIS) or Kawasaki-like syndrome associated with COVID-19 ; Мультисистемный воспалительный синдром или Кавасаки-подобный синдром у детей, ассоциированный с COVID-19

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • Contributors:
      The study did not have sponsorship; Исследование не имело спонсорской поддержки
    • بيانات النشر:
      The Rostov State Medical University
    • الموضوع:
      2023
    • Collection:
      Medical Herald of the South of Russia / Медицинский вестник Юга России
    • نبذة مختصرة :
      With the emergence of the SARS-CoV-2 virus in December 2019, all countries around the world have implemented various strategies to prevent its spread and intensively search for effective treatments. Initially, severe cases of the disease were considered only in adults, but later information appeared on the severe course of the disease in children and adolescents. This condition, which occurs as part of the transferred COVID-19, is called multisystem inflammatory syndrome (MIS) or Kawasaki-like syndrome. The available data indicate that MVS is the result of an innate and adaptive immune response characterized by a cytokine storm and a delayed immunological response to SARS-CoV-2. Epidemiological, clinical, and immunological differences classify MVS as a distinct syndrome from Kawasaki disease (БК), including age range, and geographic and ethnic distribution of patients. It should be noted that new data from patients with MVS point to unique characteristics of the immunological response, as well as clinical similarities with other inflammatory syndromes, which can serve as a guide in the search for molecular mechanisms involved in MVS. This review presents an analysis of studies on this topic: features of pathogenesis, diagnosis, treatment methods, as well as further directions for studying the problem. The search for mechanisms for the development of MVS in children continues, and, in turn, medical alertness, timely diagnosis and treatment make it possible to achieve the best possible result for such patients. ; С появлением вируса SARS-CoV-2 с декабря 2019 г. все страны мира начали активное внедрение различных стратегий для предотвращения его распространения и интенсивного поиска эффективных методов лечения. Первоначально рассматривались тяжёлые случаи заболевания только у взрослых, однако позже появилась информация о тяжёлом течении патологии у детей и подростков. Данное состояние, возникающее в рамках перенесённого COVID-19, получило название мультисистемный воспалительный синдром (МВС), или Кавасаки-подобный ...
    • File Description:
      application/pdf
    • Relation:
      https://www.medicalherald.ru/jour/article/view/1719/962; Piroth L., Cottenet J., Mariet A. S., Bonniaud P., Blot M., et al. Comparison of the characteristics, morbidity, and mortality of COVID-19 and seasonal influenza: a nationwide, population-based retrospective cohort study. Lancet Respir Med. 2021; 9 (3): 251-9. doi:10.1016/S2213-2600(20)30527-0; Kim M. M., Murthy S., Goldman R. D. Post-COVID-19 multisystem inflammatory syndrome in children. Can Fam Physician. 2021; 67 (8): 594-596. doi:10.46747/cfp.6708594; Consiglio C. R., Cotugno N., Sardh F., Pou C., Amodio D., et al. The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19. Cell. 2020; 183 (4): 968-981.e7. doi:10.1016/j.cell.2020.09.016; Abdel-Haq N., Asmar B. I., Deza Leon M. P., McGrath E. J., Arora H. S., et al. SARS-CoV-2-associated multisystem inflammatory syndrome in children: clinical manifestations and the role of infliximab treatment. Eur J Pediatr. 2021; 180 (5): 1581-1591. doi:10.1007/s00431-021-03935-1; Verdoni L., Mazza A., Gervasoni A., Martelli L., Ruggeri M., et al. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. Lancet. 2020; 395 (10239): 1771-1778. doi:10.1016/S0140-6736(20)31103-x; Schulert G. S., Blum S. A., Cron R. Q. Host genetics of pediatric SARS-CoV-2 COVID-19 and multisystem inflammatory syndrome in children. Curr Opin Pediatr. 2021; 33 (6): 549-555. doi:10.1097/MOP.0000000000001061; Sharma C., Ganigara M., Galeotti C., Burns J., Berganza F. M., et al. Multisystem inflammatory syndrome in children and Kawasaki disease: a critical comparison. Nat Rev Rheumatol. 2021; 17 (12): 731-748. doi:10.1038/s41584-021-00709-9; Chen M. R., Kuo H. C., Lee Y. J., Chi H., Li S. C., et al. Phenotype, Susceptibility, Autoimmunity, and Immunotherapy Between Kawasaki Disease and Coronavirus Disease-19 Associated Multisystem Inflammatory Syndrome in Children. Front Immunol. 2021; 12: 632890. Erratum in: Front Immunol. 2021; 12: 722582. PMID: 33732254; PMCID: PMC7959769. doi:10.3389/fimmu.2021.632890; Dufort E. M., Koumans E. H., Chow E. J., Rosenthal E. M., Muse A., et al. Multisystem Inflammatory Syndrome in Children in New York State. N Engl J Med. 2020; 383 (4): 347-358. doi:10.1056/NEJMoa2021756; Belhadjer Z., Méot M., Bajolle F., Khraiche D., Legendre A., et al. Acute Heart Failure in Multisystem Inflammatory Syndrome in Children in the Context of Global SARS-CoV-2 Pandemic. Circulation. 2020; 142 (5): 429-436. doi:10.1161/CIRCULATIONAHA.120.048360; Whittaker E., Bamford A., Kenny J., Kaforou M., Jones C. E., et al. Clinical Characteristics of 58 Children with a Pediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2. JAMA. 2020; 324 (3): 259-269. doi:10.1001/jama.2020.10369; Radujkovic A., Hippchen T., Tiwari-Heckler S., Dreher S., Boxberger M., Merle U. Vitamin D Deficiency and Outcome of COVID-19 Patients. Nutrients. 2020; 12 (9): 2757. doi:10.3390/nu12092757; Zuo T., Zhang F., Lui G. C. Y., Yeoh Y. K., Li A. Y. L., et al. Alterations in Gut Microbiota of Patients with COVID-19 During Time of Hospitalization. Gastroenterology. 2020; 159 (3): 944-955.e8. doi:10.1053/j.gastro.2020.05.048; Sperotto F., Friedman K. G., Son M. B. F., Vander Pluym C. J., Newburger J. W., Dionne A. Cardiac manifestations in SARS-CoV-2-associated multisystem inflammatory syndrome in children: a comprehensive review and proposed clinical approach. Eur J Pediatr. 2021; 180 (2): 307-322. doi:10.1007/s00431-020-03766-6; Carter M. J., Fish M., Jennings A., Doores K. J., Wellman P., et al. Peripheral immunophenotypes in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection. Nat Med. 2020; 26 (11): 1701-1707. doi:10.1038/s41591-020-1054-6; Yonker L. M., Gilboa T., Ogata A. F., Senussi Y., Lazarovits R., et al. Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier. J Clin Invest. 2021; 131 (14): e149633. doi:10.1172/JCI149633; Vella L. A., Giles J. R., Baxter A. E., Oldridge D. A., Diorio C., et al. Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19. Sci Immunol. 2021; 6 (57): eabf7570. doi:10.1126/sciimmunol.abf7570; Jones V. G., Mills M., Suarez D., Hogan C. A., Yeh D., et al. COVID-19 and Kawasaki Disease: Novel Virus and Novel Case. Hosp Pediatr. 2020; 10 (6): 537-540. doi:10.1542/hpeds.2020-0123; Diorio C., Henrickson S. E., Vella L. A., McNerney K. O., Chase J., et al. Multisystem inflammatory syndrome in children and COVID-19 are distinct presentations of SARS-CoV-2. J Clin Invest. 2020; 130 (11): 5967-5975. doi:10.1172/JCI140970; Ramaswamy A., Brodsky N. N., Sumida T. S., Comi M., Asashima H., et al. Post-infectious inflammatory disease in MIS-C features elevated cytotoxicity signatures and autoreactivity that correlates with severity. medRxiv [Preprint]. 2021: 2020. 12.01.20241364. Update in: Immunity. 2021; 54 (5): 1083-1095.e7. PMID: 33300011; PMCID: PMC7724682. doi:10.1101/2020.12.01.20241364.; Patel J. M. Multisystem Inflammatory Syndrome in Children (MIS-C). Curr Allergy Asthma Rep. 2022; 22 (5): 53-60. doi:10.1007/s11882-022-01031-4; Perez-Toledo M., Faustini S. E., Jossi S. E., Shields A. M., Marcial-Juarez E., et al. SARS-CoV-2-specific IgG1/IgG3 but not IgM in children with Pediatric Inflammatory Multi-System Syndrome. Pediatr Allergy Immunol. 2021; 32 (5): 1125-1129. doi:10.1111/pai.13504; Yonker L. M., Neilan A. M., Bartsch Y., Patel A. B., Regan J., et al. Pediatric Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Clinical Presentation, Infectivity, and Immune Responses. J Pediatr. 2020; 227: 45-52.e5. doi:10.1016/j.jpeds.2020.08.037; Cheung E. W., Zachariah P., Gorelik M., Boneparth A., Kernie S. G., et al. Multisystem Inflammatory Syndrome Related to COVID-19 in Previously Healthy Children and Adolescents in New York City. JAMA. 2020; 324 (3): 294-296. doi:10.1001/jama.2020.10374; Capone C. A., Subramony A., Sweberg T., Schneider J., Shah S., et al. Characteristics, Cardiac Involvement, and Outcomes of Multisystem Inflammatory Syndrome of Childhood Associated with severe acute respiratory syndrome coronavirus 2 Infection. J Pediatr. 2020; 224: 141-145. doi:10.1016/j.jpeds.2020.06.044; Matic K. M. SARS-CoV-2 and Multisystem Inflammatory Syndrome In Children (MIS-C). Curr Probl Pediatr Adolesc Health Care. 2021; 51 (4): 101000. doi:10.1016/j.cppeds.2021.101000; Kaushik A., Gupta S., Sood M., Sharma S., Verma S. A Systematic Review of Multisystem Inflammatory Syndrome in Children Associated with SARS-CoV-2 Infection. Pediatr Infect Dis J. 2020; 39 (11): e340-e346. doi:10.1097/INF.0000000000002888; Irfan O., Muttalib F., Tang K., Jiang L., Lassi Z. S., Bhutta Z. Clinical characteristics, treatment and outcomes of paediatric COVID-19: a systematic review and meta-analysis. Arch Dis Child. 2021; 106 (5): 440–8. Epub ahead of print. doi:10.1136/archdischild-2020-321385; Emeksiz S., Çelikel Acar B., Kibar A. E., Özkaya Parlakay A., Perk O., et al. Algorithm for the diagnosis and management of the multisystem inflammatory syndrome in children associated with COVID-19. Int J Clin Pract. 2021; 75 (9): e14471. doi:10.1111/ijcp.14471; Balasubramanian S., Nagendran T. M., Ramachandran B., Ramanan A. V. Hyper-inflammatory Syndrome in a Child with COVID-19 Treated Successfully with Intravenous Immunoglobulin and Tocilizumab. Indian Pediatr. 2020; 57 (7): 681-683. doi:10.1007/s13312-020-1901-z; Jiang L., Tang K., Levin M., Irfan O., Morris S. K., et al. COVID-19 and multisystem inflammatory syndrome in children and adolescents. Lancet Infect Dis. 2020; 20 (11): e276-e288. Erratum in: Lancet Infect Dis. 2022; 22 (10): e279. PMID: 32818434; PMCID: PMC7431129. doi:10.1016/S1473-3099(20)30651-4; Graciano-Machuca O., Villegas-Rivera G., López-Pérez I., Macías-Barragán J., Sifuentes-Franco S. Multisystem Inflammatory Syndrome in Children (MIS-C) Following SARS-CoV-2 Infection: Role of Oxidative Stress. Front Immunol. 2021; 12: 723654. doi:10.3389/fimmu.2021.723654; Zhang S. Y., Zhang Q., Casanova J. L., Su H. C.; COVID Team. Severe COVID-19 in the young and healthy: monogenic inborn errors of immunity? Nat Rev Immunol. 2020; 20 (8): 455-456. doi:10.1038/s41577-020-0373-7; Feldstein L. R., Rose E. B., Horwitz S. M., Collins J. P., Newhams M. M., et al. Multisystem Inflammatory Syndrome in U. S. Children and Adolescents. N Engl J Med. 2020; 383 (4): 334-346. doi:10.1056/NEJMoa2021680; Zeichner S. L., Cruz A. T. Multisystem Inflammatory Syndrome in Children and SARS-CoV-2 Serology. Pediatrics. 2020; 146 (6): e2020032888. doi:10.1542/peds.2020-032888; Ouldali N., Toubiana J., Antona D., Javouhey E., Madhi F., et al. Association of Intravenous Immunoglobulins Plus Methylprednisolone vs Immunoglobulins Alone with Course of Fever in Multisystem Inflammatory Syndrome in Children. JAMA. 2021; 325 (9): 855-864. Erratum in: JAMA. 2021; 326 (1): 90. PMID: 33523115; PMCID: PMC7851757. doi:10.1001/jama.2021.0694.; Henderson L. A., Canna S. W. Friedman K. G., Gorelik M., Lapidus S. K., et al. American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated with SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 1. Arthritis Rheumatol. 2020; 72 (11): 1791-1805. doi:10.1002/art.41454; Choe Y. J., Choi E. H., Choi J. W., Eun B. W., Eun L. Y., et al. Surveillance of COVID-19-Associated Multisystem Inflammatory Syndrome in Children, South Korea. Emerg Infect Dis. 2021; 27 (4): 1196-1200. doi:10.3201/eid2704.210026; https://www.medicalherald.ru/jour/article/view/1719
    • الرقم المعرف:
      10.21886/2219-8075-2023-14-2-76-83
    • Rights:
      Authors who publish with this journal agree to the following terms:Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access). ; Авторы, публикующие в данном журнале, соглашаются со следующим:Авторы сохраняют за собой авторские права на работу и предоставляют журналу право первой публикации работы на условиях лицензии Creative Commons Attribution License, которая позволяет другим распространять данную работу с обязательным сохранением ссылок на авторов оригинальной работы и оригинальную публикацию в этом журнале.Авторы сохраняют право заключать отдельные контрактные договорённости, касающиеся не-эксклюзивного распространения версии работы в опубликованном здесь виде (например, размещение ее в институтском хранилище, публикацию в книге), со ссылкой на ее оригинальную публикацию в этом журнале.Авторы имеют право размещать их работу в сети Интернет (например в институтском хранилище или персональном сайте) до и во время процесса рассмотрения ее данным журналом, так как это может привести к продуктивному обсуждению и большему количеству ссылок на данную работу (См. The Effect of Open Access).
    • الرقم المعرف:
      edsbas.DF47BD5F