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Multisystem inflammatory syndrome (MIS) or Kawasaki-like syndrome associated with COVID-19 ; Мультисистемный воспалительный синдром или Кавасаки-подобный синдром у детей, ассоциированный с COVID-19
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- المؤلفون: E. A. Besedina; A. S. Badyan; S. G. Piskunova; E. V. Dudnikova; V. N. Kovalenko; A. M. Inkin; Е. А. Беседина; А. С. Бадьян; С. Г. Пискунова; Э. В. Дудникова; В. Н. Коваленко; А. М. Инкин
- المصدر:
Medical Herald of the South of Russia; Том 14, № 2 (2023); 76-83 ; Медицинский вестник Юга России; Том 14, № 2 (2023); 76-83 ; 2618-7876 ; 2219-8075 ; 10.21886/2219-8075-2023-14-2- الموضوع:
- نوع التسجيلة:
article in journal/newspaper- اللغة:
Russian - المصدر:
- معلومة اضافية
- Contributors: The study did not have sponsorship; Исследование не имело спонсорской поддержки
- بيانات النشر: The Rostov State Medical University
- الموضوع: 2023
- Collection: Medical Herald of the South of Russia / Медицинский вестник Юга России
- نبذة مختصرة : With the emergence of the SARS-CoV-2 virus in December 2019, all countries around the world have implemented various strategies to prevent its spread and intensively search for effective treatments. Initially, severe cases of the disease were considered only in adults, but later information appeared on the severe course of the disease in children and adolescents. This condition, which occurs as part of the transferred COVID-19, is called multisystem inflammatory syndrome (MIS) or Kawasaki-like syndrome. The available data indicate that MVS is the result of an innate and adaptive immune response characterized by a cytokine storm and a delayed immunological response to SARS-CoV-2. Epidemiological, clinical, and immunological differences classify MVS as a distinct syndrome from Kawasaki disease (БК), including age range, and geographic and ethnic distribution of patients. It should be noted that new data from patients with MVS point to unique characteristics of the immunological response, as well as clinical similarities with other inflammatory syndromes, which can serve as a guide in the search for molecular mechanisms involved in MVS. This review presents an analysis of studies on this topic: features of pathogenesis, diagnosis, treatment methods, as well as further directions for studying the problem. The search for mechanisms for the development of MVS in children continues, and, in turn, medical alertness, timely diagnosis and treatment make it possible to achieve the best possible result for such patients. ; С появлением вируса SARS-CoV-2 с декабря 2019 г. все страны мира начали активное внедрение различных стратегий для предотвращения его распространения и интенсивного поиска эффективных методов лечения. Первоначально рассматривались тяжёлые случаи заболевания только у взрослых, однако позже появилась информация о тяжёлом течении патологии у детей и подростков. Данное состояние, возникающее в рамках перенесённого COVID-19, получило название мультисистемный воспалительный синдром (МВС), или Кавасаки-подобный ...
- File Description: application/pdf
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- الرقم المعرف: 10.21886/2219-8075-2023-14-2-76-83
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- الرقم المعرف: edsbas.DF47BD5F
- Contributors:
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