Contributors: University of Nevada Reno; Medical University of Plovdiv; Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO); University of California San Francisco (UC San Francisco); University of California (UC); Vieillissement et Maladies chroniques : approches épidémiologique et de santé publique (VIMA); Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM); Cohortes épidémiologiques en population (CONSTANCES); Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Université Paris Cité (UPCité); Hôpital Raymond Poincaré AP-HP; Institut de recherche en santé, environnement et travail (Irset); Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique EHESP (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ); California Environmental Protection Agency; Gachon University; Università degli Studi di Modena e Reggio Emilia = University of Modena and Reggio Emilia (UNIMORE); McMaster University Hamilton, Ontario; National Pension Research Institute Jeonju-si; Oswaldo Cruz Foundation; Chinese Center for Disease Control and Prevention; 70672; National Institute for Occupational Safety and Health, NIOSH: 1E11OH0010676-02, 5NE11OH010461-03–00, 6NE11OH010461-02–01; World Health Organization, WHO; International Labour Organisation, ILO; Lancaster University; Bundesministerium für Gesundheit, BMG; Agencia Española de Cooperación Internacional para el Desarrollo, AECID; All authors are salaried staff members of their respective institutions. This publication was prepared with financial support to the World Health Organization from the National Institute for Occupational Safety and Health of the Centres for Disease Control and Prevention of the United States of America (Grant 1E11OH0010676-02; Grant 6NE11OH010461-02–01; and Grant 5NE11OH010461-03–00); the German Federal Ministry of Health (BMG Germany) under the BMG-WHO Collaboration Programme 2020–2023 (WHO specified award ref. 70672); and the Spanish Agency for International Cooperation (AECID) (WHO specified award ref.71208). The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.; We thank Dr Paul Whaley (Editor, Systematic Reviews, Environment International; and Lancaster University) for the editorial review and guidance. Dr Kurt Straif (at the time: WHO IARC) contributed to the early stages of this systematic review. Dr Yuka Ujita and then Dr Halim Hamzaoui were the ILO focal point for the WHO/ILO Joint Estimates. Dr Nathan DeBono (WHO IARC), Bayan Hosseini (WHO IARC), Dr Ann Olsson (WHO IARC), and Professor Lesley Stayner (WHO IARC) provided comments on an earlier version of the manuscript.
نبذة مختصرة : International audience ; Background: The World Health Organization (WHO) and the International Labour Organization (ILO) are the producers of the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury (WHO/ILO Joint Estimates). Welding fumes have been classified as carcinogenic to humans (Group 1) by the WHO International Agency for Research on Cancer (IARC) in IARC Monograph 118; this assessment found sufficient evidence from studies in humans that welding fumes are a cause of lung cancer. In this article, we present a systematic review and meta-analysis of parameters for estimating the number of deaths and disability-adjusted life years from trachea, bronchus, and lung cancer attributable to occupational exposure to welding fumes, to inform the development of WHO/ILO Joint Estimates on this burden of disease (if considered feasible).Objectives: We aimed to systematically review and meta-analyse estimates of the effect of any (or high) occupational exposure to welding fumes, compared with no (or low) occupational exposure to welding fumes, on trachea, bronchus, and lung cancer (three outcomes: prevalence, incidence, and mortality).Data sources: We developed and published a protocol, applying the Navigation Guide as an organizing systematic review framework where feasible. We searched electronic databases for potentially relevant records from published and unpublished studies, including Medline, EMBASE, Web of Science, CENTRAL and CISDOC. We also searched grey literature databases, Internet search engines, and organizational websites; hand-searched reference lists of previous systematic reviews; and consulted additional experts.Study eligibility and criteria: We included working-age (≥15 years) workers in the formal and informal economy in any Member State of WHO and/or ILO but excluded children (<15 years) and unpaid domestic workers. We included randomized controlled trials, cohort studies, case-control studies, and other non-randomized intervention studies with an estimate of the effect ...
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