نبذة مختصرة : Objectives: Exercise is an integral part of diabetes care. In Iranian women with type II diabetes, we compared the effects of supervised group exercise therapy with the effects of home-based exercise therapy on health-related quality of life (HRQOL), anthropometric parameters, glycaemic control and lipid profile. Materials and methods: One hundred and two diabetic women were randomised to supervised and home-based groups. Methods: Over 12 weeks, participants received supervised group-exercise therapy or a home-based exercise-therapy program. During the intervention, they were assessed three times: at baseline, and at weeks 6 and 12. Generalized Estimating Equation models were used to examine the associations between the type of exercise-therapy program and changes over time in anthropometric and biochemical outcomes, and in HRQOL scales of SF36 questionnaire. Results: Relative to home-based group, supervised group improved significantly regarding role-physical, general health, mean body weight and body mass index from baseline to week 12 (p = 0.01). Their reduction in mean body-fat mass from baseline to week 6 (p = 0.04) was greater. Similarly, their role-physical, general health and role-emotional improved significantly during the intervention (p < 0.05). From baseline to the twelfth week, the HbA1c level fell significantly (p < 0.05) in both groups. Conclusions: Supervised group-exercise therapy was more effective than home-based exercise therapy in improving HRQOL and body composition in diabetic women. However, home-based exercise therapy also produced significant improvements in glycaemic control, body composition and lipid profile. Whether in a supervised or home-based setting, the exercise intervention can therefore be effective in improving health outcomes in diabetic patients. © 2016 Diabetes India
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