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Impairment of Rat Fetal Beta-Cell Development by Maternal Exposure to Dexamethasone during Different Time-Windows.

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  • معلومة اضافية
    • Contributors:
      UCL - SST/ISV - Institut des sciences de la vie
    • بيانات النشر:
      Public Library of Science
    • الموضوع:
      2011
    • Collection:
      DIAL@UCL (Université catholique de Louvain)
    • نبذة مختصرة :
      Glucocorticoids (GCs) take part in the direct control of cell lineage during the late phase of pancreas development when endocrine and exocrine cell differentiation occurs. However, other tissues such as the vasculature exert a critical role before that phase. This study aims to investigate the consequences of overexposure to exogenous glucocorticoids during different time-windows of gestation for the development of the fetal endocrine pancreas.
    • ISSN:
      1932-6203
    • Relation:
      boreal:90889; http://hdl.handle.net/2078.1/90889; info:pmid/21991320; urn:ISSN:1932-6203
    • الرقم المعرف:
      10.1371/journal.pone.0025576
    • الدخول الالكتروني :
      http://hdl.handle.net/2078.1/90889
      https://doi.org/10.1371/journal.pone.0025576
    • Rights:
      info:eu-repo/semantics/openAccess
    • الرقم المعرف:
      edsbas.D6FBADA3