Association of intake of thiamine, riboflavin and niacin with periodontitis among Korean adults ; 한국 성인에서 티아민 리보플라빈 및 나이아신 섭취의 치주염에 대한 연관성

학위논문(박사)--서울대학교 대학원 :치의학대학원 치의과학과,2020. 2. 김현덕. ; Objective: Adequate intake of vitamin B-complex could be important for oral health. However, few studies reported on the association of individual thiamine (vitamin B1), riboflavin (vitamin B2), and niacin (vitamin B3) with periodontal health. This study described the association between periodontal health and dietary vitamin B1, B2, and B3 intake in the Korean population. Methods: 12,750 adults aged over 19 years were included for this study as a sub-sample of the national data set from Korean National Health and Nutrition Examination Survey (IV and V). Periodontitis and gingivitis were defined as Community Periodontal Index (CPI) scores of 3-4 and 1-2, respectively. Informations on dietary vitamin B1, B2, and B3 intake were from 24-hour-dietary recall method. Multi-variable complex logistic regression analyses estimated association between vitamin B1, B2, and B3 intakes and periodontal status after adjusting for various potential confounders. Stratified analyses by age, sex, dyslipidemia and total energy intake were also undertaken. Results: The weighted prevalence of periodontitis (CPI 3-4) and gingivitis (CPI 1-2) was 29.9% and 46.6%, respectively. Our data showed none of the inadequate intake of vitamin B1, B2, and B3 with gingivitis and vitamin B1, B2 with periodontitis showed the significant association after adjusting for various potential confounders. However, inadequate intake of vitamin B3 showed the significant association with periodontitis by quartile and EAR (adjusted odds ratio (aOR) of vitamin B3 by EAR =1.25, 95% CI=1.07-1.46). The association of vitamin B3 with periodontitis was stronger in females and participants aged 40-59 years. Conclusions: Inadequate dietary intake of vitamin B3 was associated with periodontitis. ; 1. 연구목적 적절한 비타민 B 복합체의 섭취는 건강에 필수적이다. 그러나, 비타민 B 복합체에 속하는 티아민(Thiamine, 비타민 B1) 리보플라빈(Riboflavin, 비타민 B2) 및 나이아신(Niacin, 비타민 B3)과 치주질환의 연관성에 관한 연구는 아직 부족하다. 따라서, 본 연구의 목적은 한국 성인에서 비타민 B1, B2, B3 섭취와 치주질환의 연관성을 평가함이다. 2. 연구 대상 및 ...