Contributors: Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC); Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD Occitanie )-Université de Montpellier (UM); Laboratoire des Interactions Virus-Hôtes Cayenne, Guyane Française; Institut Pasteur de la Guyane; Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur); Michigan State University East Lansing; Michigan State University System; Mississippi State University Mississippi; Centre Hospitalier Andrée Rosemon Cayenne, Guyane Française; Centre d'Investigation Clinique Antilles-Guyane (CIC - Antilles Guyane); Université des Antilles et de la Guyane (UAG)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pointe-à-Pitre / Abymes Guadeloupe -CHU de Fort de France-Centre Hospitalier Andrée Rosemon Cayenne, Guyane Française; Unité Mixte de Recherche d'Épidémiologie des maladies Animales et zoonotiques (UMR EPIA); VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE); Université Clermont Auvergne (UCA); Université de Lyon; This work was supported by the joint NSF-NIH-NIFA Ecology and Evolution of Infectious Disease program (DEB grant number 1911457). CC, BdT, and J-FG benefited from an Investissement d’Avenir grant managed by Agence Nationale de la Recherche (LABEX CEBA: ANR-10-LABX-25-01). CC was supported by Institut de Recherche pour le Développement (IRD), Centre National pour la Recherche Scientifique, and Université de Montpellier (UM). J-FG was supported by IRD, UM, Institut national de Recherches pour l’Agriculture, l’Alimentation et l’Environnement, and Ecole des Hautes Etudes en Santé Publique. MEB received an award from an Investissement d’Avenir grant managed by Agence Nationale de la Recherche (LABEX CEMEB: ANR-10-LABX-04-01) and support by Michigan State Agbioresearch, College of Agriculture and Natural Resources, Department of Entomology, and Department of Osteopathic Medical Specialties. PLT benefited from a grant managed by Agence Nationale de la Recherche sur le sida et les hépatites virales/Maladies Infectieuses Emergentes (ANRS MIE).; ANR-10-LABX-0025,CEBA,CEnter of the study of Biodiversity in Amazonia(2010); ANR-10-LABX-0004,CeMEB,Mediterranean Center for Environment and Biodiversity(2010)
نبذة مختصرة : International audience ; Predicting the outbreak of infectious diseases and designing appropriate preventive health actions require interdisciplinary research into the processes that drive exposure to and transmission of disease agents. In the case of mycobacterial diseases, the epidemiological understanding of the scientific community hitherto was based on the clinical studies of infections in vertebrates. To evaluate the information gained by comprehensively accounting for the ecological and evolutionary constraints, we conducted literature searches assessing the role of mycobacteria interactions with non-vertebrate species in the origin of their pathogenicity and variations in disease risk. The reviewed literature challenges the current theory of person-to-person transmission for several mycobacterial infections. Furthermore, the findings suggest that diverse non-vertebrate organisms influence virulence, mediate transmission, and contribute to pathogen abundance in relation to vertebrate exposure. We advocate that an ecological and evolutionary framework provides novel insights to support a more comprehensive understanding of the prevention and management of diseases in vertebrates.
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