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Association between reported work in cold environments and stroke occurrence in the CONSTANCES cohort: a prospective study

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  • معلومة اضافية
    • Contributors:
      Institut de recherche en santé, environnement et travail (Irset); Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique EHESP (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ); Donald and Barbara Zucker School of Medicine at Hofstra/Northwell; Hofstra University Hempstead; Laboratoire de Psychologie des Pays de la Loire (LPPL); Université d'Angers (UA)-Nantes Université - UFR Lettres et Langages (Nantes Univ - UFR LL); Nantes Université - pôle Humanités; Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Humanités; Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ); Translational Innovation in Medicine and Complexity / Recherche Translationnelle et Innovation en Médecine et Complexité - UMR 5525 (TIMC ); VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ); Université Grenoble Alpes (UGA); UMS 011; Institut National de la Santé et de la Recherche Médicale (INSERM); Cohortes épidémiologiques en population (CONSTANCES); Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Université Paris Cité (UPCité); The study was funded by the Interuniversity Institution of Occupational Health of Paris Ile-de-France, which had no role in the collection of data, analyses and the writing of the manuscript. The CONSTANCES Cohort Study was supported and funded by the Caisse Nationale d’Assurance Maladie; it is an ‘Infrastructure Nationale en Biologie et Santé’ and benefits from ANR (ANR-11-INBS-0002) grant funding. CONSTANCES is also partly funded by MSD, AstraZeneca and Lundbeck.; ANR-11-INBS-0002,CONSTANCES,La cohorte CONSTANCES - Infrastructure épidémiologique ouverte pour la recherche et la surveillance(2011)
    • بيانات النشر:
      HAL CCSD
      BMJ Publishing Group
    • الموضوع:
      2022
    • Collection:
      Université de Rennes 1: Publications scientifiques (HAL)
    • نبذة مختصرة :
      International audience ; Objective Cold environments are a potential risk factor for stroke. The aim of this study was to investigate the association between performing work tasks in cold environments and the occurrence of a first stroke event. Methods From the French population-based cohort CONSTANCES (‘ Cohorte des consultants des Centres d'examens de santé ’ in French), we collected data from baseline questionnaires along with medical interviews on cardiovascular risk factors and reported exposure to cold temperatures (<10°C) at work. Exposures were categorised as rare (<2 hours/day), often (≥2 and <4 hours/day) and almost always (≥4 hours/day). Incidence of stroke was retrieved from the French National Health database. Bivariate and multivariable logistic regression models were used to assess the association between working in cold environments and the incidence of stroke. Stratified analyses on stroke types were also conducted. Results There were 160 782 participants and 224 strokes (168 ischaemic and 76 haemorrhagic) included in our study. No significant increase in stroke was found for working in cold environments; the adjusted OR for often or almost always exposed was 1.14 (95% CI 0.46 to 2.84). Conclusions This study did not reveal a significant excess risk of stroke for occupational exposures to low temperatures. Further studies are needed to better assess the effect of preventive measures and very low temperature on occurrence of cardiovascular diseases.
    • Relation:
      hal-03738094; https://hal.science/hal-03738094; https://hal.science/hal-03738094/document; https://hal.science/hal-03738094/file/e054198.full.pdf
    • الرقم المعرف:
      10.1136/bmjopen-2021-054198
    • Rights:
      http://creativecommons.org/licenses/by-nc/ ; info:eu-repo/semantics/OpenAccess
    • الرقم المعرف:
      edsbas.D35AFD69