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Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis.

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  • معلومة اضافية
    • بيانات النشر:
      Nature Publishing Group
    • الموضوع:
      2008
    • Collection:
      University of Bedfordshire Repository
    • نبذة مختصرة :
      To better understand the dual, tumour-suppressive and tumour-promoting function of transforming growth factor-beta (TGFbeta), we analysed mammary epithelial NMuMG cells in response to short and long-term TGFbeta exposure.
    • ISSN:
      1476-5594
    • Relation:
      http://www.ncbi.nlm.nih.gov/pubmed/17724470; http://www.nature.com/onc/journal/v27/n9/full/1210741a.html; Gal, A., Sjöblom, T., Fedorova, L., Imreh, S., Beug, H. and Moustakas, A. (2008) 'Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis', 'Oncogene', 27(9),pp. 1218-1230.; http://hdl.handle.net/10547/294523; Oncogene
    • الرقم المعرف:
      10.1038/sj.onc.1210741
    • الرقم المعرف:
      edsbas.D2A3298A