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Updates on World Health Organization Classification and Staging of oesophageal tumours: Implications for future clinical practice

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اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • بيانات النشر:
      Elsevier
    • الموضوع:
      2020
    • Collection:
      Griffith University: Griffith Research Online
    • نبذة مختصرة :
      The Fifth edition of the World Health Organization Classification of Digestive system and American Joint Committee on Cancer (AJCC) staging manual contain substantial refinements of information for oesophageal tumours. The epithelial tumours of oesophagus are classified as benign, dysplasia and malignant groups. Dysplasia is divided into Barrett dysplasia and squamous dysplasia and graded into either low grade or high grade. Malignant oesophageal tumours are often adenocarcinoma or squamous cell carcinoma. The main update in cancer staging in oesophageal tumours is the subdivision of the prognostic staging into 3 groups; squamous cell carcinoma, adenocarcinoma and carcinoma after adjuvant therapy. HER-2 amplification is recognized as a molecular target for therapy of oesophagogastric adenocarcinoma. The other oesophageal tumours are adenoid cystic carcinoma, mucoepidermoid/adenosquamous carcinoma, undifferentiated carcinoma and neuroendocrine neoplasms. Overall, the incorporation of new data and definitions on histopathology, prognostic factors and genetics are important for personalized management of patients with oesophageal tumours. ; Full Text
    • ISSN:
      0046-8177
    • Relation:
      Human Pathology; Lam, AK-Y, Updates on World Health Organization Classification and Staging of oesophageal tumours: Implications for future clinical practice, Human Pathology, 2020; http://hdl.handle.net/10072/399383
    • الرقم المعرف:
      10.1016/j.humpath.2020.10.015
    • الدخول الالكتروني :
      http://hdl.handle.net/10072/399383
      https://doi.org/10.1016/j.humpath.2020.10.015
    • Rights:
      http://creativecommons.org/licenses/by-nc-nd/4.0/ ; © 2020 Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited. ; open access
    • الرقم المعرف:
      edsbas.D13CD192