Congenital co-infection with different Trypanosoma cruzi lineages

Artículo de publicación ISI ; Variability of mixed Trypanosoma cruzi congenital infection in Chile in twenty one congenital samples of Chagas disease is reported. Recognition of infecting strains was performed by minicircle hybridization tests. Seven newborns with double infection were found. Trypanosoma cruzi TcII and TcV lineages were the most frequent in single and mixed infections. With these results we pretend to understand the epidemiological significance of the T. cruzi lineages forwhich the placenta does not seemto represent an actual barrier in congenital infections. ; This work was supported by SIDA-SAREC (Sweden) grant. Chemotherapeutical treatment was financially supported by the Chilean Ministry of Health.