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What does not kill you makes you stronger: surviving anti-cancer therapies by cytoskeletal remodeling and Myosin II reactivation.

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  • معلومة اضافية
    • بيانات النشر:
      Molecular & Cellular Oncology
    • الموضوع:
      2020
    • Collection:
      Universidad Francisco de Vitoria: Depósito Digital FV (DDFV)
    • نبذة مختصرة :
      Myosin II and its regulator Rho-associated coiled-coil containing protein kinase (ROCK) are essential for cell invasion and metastatic dissemination. Our recent findings show that this molecular machinery is also involved in drug resistance in melanoma by playing a dual role: protection of tumor cells from reactive oxygen species (ROS) and DNA damage (intrinsic), and co-option of myeloid and lymphoid populations to establish immunosuppression (extrinsic). ; post-print ; 1758 KB
    • ISSN:
      2372-3556
    • Relation:
      http://hdl.handle.net/10641/2302
    • الرقم المعرف:
      10.1080/23723556.2020.1735911
    • الدخول الالكتروني :
      http://hdl.handle.net/10641/2302
      https://doi.org/10.1080/23723556.2020.1735911
    • Rights:
      Atribución-NoComercial-SinDerivadas 3.0 España ; http://creativecommons.org/licenses/by-nc-nd/3.0/es/ ; openAccess
    • الرقم المعرف:
      edsbas.D117E38A