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Two decades of valve-sparing root reimplantation in tricuspid aortic valve: impact of aortic regurgitation and cusp repair.

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  • معلومة اضافية
    • Contributors:
      UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire; UCL - (SLuc) Service de chirurgie cardiovasculaire et thoracique; UCL - (SLuc) Service d'anesthésiologie
    • بيانات النشر:
      Oxford University Press
    • الموضوع:
      2021
    • Collection:
      DIAL@USL-B (Université Saint-Louis, Bruxelles)
    • نبذة مختصرة :
      OBJECTIVES: Our goal was to analyse the influence of preoperative aortic regurgitation (AR) on the necessity of cusp repair during valve-sparing reimplantation (VSR). We focused on patients with tricuspid aortic valves (TAV) and evaluated the impact of AR and cusp repair on long-term outcomes. METHODS: From March 1998 to December 2018, a total of 512 consecutive patients underwent VSR at our institution; of these, 303 had a TAV. The mean age was 53 ± 15 years, and the median follow-up was 6.12 years. The rate and type of cusp repair were analysed based on preoperative AR. Time-to-event analysis was performed, as well as risk of death, reoperation and AR recurrence. RESULTS: Cusp repair was necessary in 168 (55.4%) patients; the rate rose significantly as AR grade increased (P < 0.001). In-hospital mortality was 1% (n = 3). At 5 and 10 years, overall survival was 92 ± 2% and 75 ± 5%, respectively. Freedom from valve reoperation was 95 ± 2% and 90 ± 3%. Freedom from AR >2+ and AR >1+ at 10 years was 88 ± 4% and 70.4 ± 4.6%, respectively. Independent predictors of death included age, New York Heart Association functional class and type-A aortic dissection. Predictors of AR greater than mild included previous cardiac surgery and severe preoperative AR. CONCLUSION: In patients with TAV receiving VSR, the necessity of cusp repair increased with the degree of preoperative AR. Preoperative AR and cusp repair do not impact long-term survival and aortic valve reoperation, but severe preoperative AR and multiple cusp repair increase the risk of recurrent moderate-to-severe AR. Overall, cusp repair seems to attenuate the negative impact of preoperative AR for at least 1 decade in a majority of patients.
    • ISSN:
      1010-7940
      1873-734X
    • Relation:
      boreal:251212; http://hdl.handle.net/2078.1/251212; info:pmid/33332548; urn:ISSN:1010-7940; urn:EISSN:1873-734X
    • الرقم المعرف:
      10.1093/ejcts/ezaa427
    • Rights:
      info:eu-repo/semantics/openAccess
    • الرقم المعرف:
      edsbas.CBF10608