Functional coatings on Ti-6A1-4V and NiTi shape memory alloy for medical applications

Due to its excellent biocompatibility and mechanical properties, Ti-6Al-4V alloy has been extensively used in the medical field, especially as a material for hard tissue replacement. Owing to the unique shape memory and superelastic properties, NiTi shape memory alloy (SMA, with 50.8 at.% of Ni) has been investigated for load-bearing applications in orthopedics and dentistry. Since the longevity of current metal implants is approximately 10 to 15 years, many patients need to have revision surgeries in their lifetime. Therefore, there is great interest in the long-term stability, biocompatibility, bioactivity and other properties of Ti-6Al-4V and NiTi SMA implants. Implant-associated infections also pose serious threat to the success of metal implants. The goal of this project was to investigate several low-temperature surface modification techniques, including anodization and electrochemical deposition, and formulate coatings for potential clinical applications. Accordingly, several types of coatings were synthesized on Ti-6Al-4V and NiTi SMA substrates. Various aspects of the coatings, such as morphology, chemical composition, crystallinity, phase and bioactivity, were analyzed. Firstly, a systematic study on the formation of titania nanotubes on Ti-6Al-4V by anodization was performed. Anodizing voltage and time were varied for comparisons. A dense and compact titania nanotube layer was synthesized on Ti-6Al-4V by anodizing at 25 V for 20 min. The titania nanotubes formed were rutile. After annealing at 500oC for 1 h, the titania nanotubes became anatase. The anatase phase exhibited better wettability than the rutile phase. Secondly, dense and compact apatite coatings were formed on NiTi SMA samples through electrochemical deposition using mainly double-strength simulated body fluid (2SBF) as the electrolyte. The deposition conditions were varied and apatite coating characteristics studied. With the inclusion of collagen molecules (0.1 mg/ml) in the electrolyte (2SBFC), apatite/collagen composite coatings were ...