Das synaptische Vesikelrecycling: Molekulare Funktionen des AP-1-Komplexes und seiner σ1B-Adaptinuntereinheit ; Synaptic vesicle recycling: Molecular functions of the AP-1 complex subunit σ1B-adaptin
Schu, Peter Prof. Dr.; Steinem, Claudia Prof. Dr.; Wienands, Jürgen Prof. Dr.
الموضوع:
2013
Collection:
Georg-August-Universität Göttingen: eDiss
نبذة مختصرة :
The heterotetrameric AP-1-complex is localized to trans-Golgi-Network (TGN) and early endosomes. It mediates specific clathrin-dependant vesicular pathways. In vertebrates three isoforms of its σ1 subunit are expressed: A, B and C. σ1A is ubiquitously expressed, while σ1B and σ1C are expressed in a tissue specific pattern. σ1B shows highest expression in brain. The phenotype of AP-1/σ1B- ; 2013-02-03
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