Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Recent Developments in Biologic Therapies for the Treatment of Patients with Systemic Lupus Erythematosus

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • بيانات النشر:
      Oxford University Press
    • الموضوع:
      2019
    • Collection:
      Repositório do Centro Hospitalar de Lisboa Central EPE
    • نبذة مختصرة :
      SLE has a complex pathogenesis, and multiple therapeutic targets have been discovered in recent years. In spite of belimumab being approved by the US Food and Drug Administration and the widespread use of rituximab, there have been many failed attempts to treat SLE successfully using biologic agents. In this review, we consider newer biologic approaches that might offer the hope of improving the outcome of SLE patients. These include the fully humanized anti-CD20 mAbs, PEGylated anti-CD40L, IFNα inhibitors, rigerimod and immune complexes blockade. ; info:eu-repo/semantics/publishedVersion
    • Relation:
      Rheumatology (Oxford). 2019 Mar 1;58(3):382-387.; http://hdl.handle.net/10400.17/3913
    • الدخول الالكتروني :
      http://hdl.handle.net/10400.17/3913
    • Rights:
      openAccess
    • الرقم المعرف:
      edsbas.C5CB0493