Prevalence of Anxiety and Depression in Infertile Women in Siriraj Hospital by using Thai Hospital Anxiety and Depression Scale

Objectives: To identify the prevalence of anxiety and depression in infertile women at Siriraj Hospital using Thai Hospital Anxiety and Depression Scale (Thai HADS) and to identify the risk factors of anxiety and depression. Materials and Methods: All the patients who attended at infertile clinic during July 2016 to February 2017 received the questionnaires that consisted of demographic information and Thai HADS questionnaire. The consent occurred when the participant gave the questionnaires back after completing. Potential risks were compared by Chi square and analysis of variance test. Results: From 500 questionnaires, 421 were returned. The mean age was 36.5 years old and 61.3% had income ≥ 50,000 baht. Previous treatment failure was 71.3% (300/421) which 59% (177/300) had treatment failure ≥ 3 times. The prevalence of anxiety and depression were 13% and 3%, respectively. Factors that significantly lead to anxiety were duration of infertility 5 years or more, previous infertility treatment failure, previously failed in vitro fertilization (IVF) and the number of treatment failure ≥ 3 times. The relative risks of anxiety were 1.88, 2.37, 1.72 and 2.61, respectively. Conclusion: Prevalence of anxiety and depression in infertile women at Siriraj Hospital by using Thai HADS was 13% and 3%. Duration of infertility ≥ 5 years, previous treatment failure, previously failed IVF and the number of treatment failure ≥ 3 times increased anxiety significantly.