نبذة مختصرة : Osim što je nužna za život, hrana uvelike utječe na sve aspekte čovjekova života, najviše na zdravlje. Pravilna prehrana ispunjena raznolikom i zdravom hranom posebno biljnim vrstama bogatim fitokemikalijama, osigurava veliku otpornost organizma na različita oboljenja pa tako i na karcinom. Suočen s velikim porastom kroničnih bolesti čovjek sve češće odabire zdravu prehranu i prirodne lijekove s ciljem prevencije različitih oboljenja. U ovom radu istražit će se antiproliferativna aktivnost mikrovalnih ekstrakata crne i smeđe gorušice na stanice karcinoma dojke (MDA MB 231) i mokraćnog mjehura (TCC SUP). Ekstrakti dobiveni metodom mikrovalne ekstrakcije su analizirani plinskom kromatografijom-masenom spektormetrijom (GC-MS) da bi se identificirao dominantan spoj. Potom je MTT testom vršeno mjerenje njihove citotoksične aktivnosti te su dobiveni rezultati aktivnosti s obzirom na razliku u koncentraciji i na period inkubacije ekstrakata. ; Besides being essential for life, food greatly affects all the aspects of human life, mostly to health. Proper nutrition based on healthy food especially with plant species that contain phytochemicals, provides high resistance of the body to various diseases, including cancer. Faced with a huge increase in chronic diseases, man is increasingly choosing healthy nutrition and natural medicines in the prevention of various diseases. This study examines antiproliferative activity of black and brown micowave mustard seeds extracts on breast (MDA MB 231) and bladder (TCC SUP) cancer cells. Extracts obtained by the microwave extraction method are analyzed by gas chromatography-mass spectometry (GC-MS) to identify the dominant compound. Then MTT test measured their cytotoxic activity and so the results were obtained considering the difference in concentration and in incubation period.
Processing Request
No Comments.