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Rifampicin-induced thrombocytopenia ; Trombocitopenia inducida por rifampicina

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  • معلومة اضافية
    • بيانات النشر:
      Universidad de Antioquia
    • الموضوع:
      2018
    • Collection:
      Universidad de Antioquia: Sistema de Revistas
    • نبذة مختصرة :
      Rifampicin-induced thrombocytopenia is a rare but potentially fatal immune phenomenon. We report the case of an immunocompromised patient with disseminated tuberculosis who developed rifampicin-induced thrombocytopenia 12 hours after starting anti-tuberculous therapy without previous drug sensitization. The cause-effect relationship was confirmed when thrombocytopenia resolved with rifampicin suspension but later reappeared upon drug re-exposure. ; La trombocitopenia inducida por rifampicina es un fenómeno de origen inmune cuya presentación es inusual pero potencialmente fatal. Se presenta el caso de un paciente inmunocomprometido y con tuberculosis diseminada quien desarrolló trombocitopenia inducida por rifampicina en las primeras 12 horas tras inicio de la terapia antituberculosa sin que mediara sensibilización previa al medicamento. Se confirmó la relación de causa-efecto al resolverse la trombocitopenia con la suspensión de la rifampicina y al reaparecer con la re-exposición al fármaco.
    • File Description:
      application/pdf; application/xml
    • Relation:
      https://revistas.udea.edu.co/index.php/iatreia/article/view/327106/20786724; https://revistas.udea.edu.co/index.php/iatreia/article/view/327106/20795282; https://revistas.udea.edu.co/index.php/iatreia/article/view/327106
    • الدخول الالكتروني :
      https://revistas.udea.edu.co/index.php/iatreia/article/view/327106
    • Rights:
      Derechos de autor 2018 Universidad de Antioquia ; https://creativecommons.org/licenses/by-nc-sa/4.0
    • الرقم المعرف:
      edsbas.B40E5B66