Low frequency lung resistance is a global bronchoconstriction detection measure, but is still sensitive to small airways disease

The Forced Oscillation Technique (FOT) is experiencing increased uptake as a clinical measure of lung function and airway constriction. However, due to the complex nature of test outputs, there is still uncertainty about exactly how test indices from the FOT respond to specific types of lung disease, such as bronchoconstriction and tissue breakdown. By comparing correlations of clinical and simulated data, we provide evidence of the nature of these responses.