Effect of different types of exercise on quality of life in breast cancer patients and survivors : an umbrella review

Purpose: To present an umbrella review on previous meta-analysis and systematic reviews addressing the relationship between quality of life (QoL) among breast cancer (BC) patients and survivors and exercise. Methods: Pubmed, Web of Science, the Cochrane Library, and PEDro databases were searched to identify relevant systematic reviews and meta-analyses. Reviews assessing exercise interventions on QoL as one of the primary outcomes in breast cancer patients and survivors were included. The Grade of Recommendation, Assessment, Development, and Evaluation (GRADE) tool was used to evaluate the quality of evidence. The methodological quality of the included studies were evaluated by the Assessment of Methodologic Quality of Systematic Reviews (AMSTAR) appraisal. Results: Twenty-five studies met all the inclusion criteria. The AMSTAR score varied from 3 to 11 points with an overall mean of 7.4 points. Out of 25 studies, 23 found beneficial effects of aerobic, resistance, combined, and mind and body exercise in BC patients and survivors, and 2 reported no effects of exercise on QoL. As for GRADE, 7 studies were rated as “high”, 10 as “moderate, 6 as “low”, and 2 as “very low”. Conclusion: Exercise of any kind can be regarded as beneficial to QoL in BC patients and survivors. Mind and body exercise is emerging as a viable option in the BC field and has shown to have the same benefits as the more conventional forms of exercise. More high-quality studies are needed in BC patients at any stage and BC survivors. ; Objetivo: Apresentar uma umbrella review de revisões sistemáticas e meta-análises anteriores que abordem a relação entre qualidade de vida em pacientes e sobreviventes de cancro da mama e exercício. Métodos: As bases de dados da Pubmed, Web of Science, the Cochrane Library, e PEDro database foram usadas para identificar revisões sistemáticas e meta-análises relevantes. As revisões que analisavam as intervenções de exercício com a qualidade de vida como um dos outcomes principais em pacientes e sobreviventes de ...