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Relevant Biomarkers in Medical Practices: An Analysis of the Needs Addressed by an International Survey

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  • معلومة اضافية
    • Contributors:
      Centre hospitalier régional Metz-Thionville (CHR Metz-Thionville); Georgia Tech Lorraine Metz; Ecole Nationale Supérieure des Arts et Metiers Metz-Georgia Institute of Technology Atlanta -Ecole Supérieure d'Electricité - SUPELEC (FRANCE)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC); Université Bourgogne Franche-Comté COMUE (UBFC)-Université Bourgogne Franche-Comté COMUE (UBFC); Équipe Microsystèmes électromécaniques (LAAS-MEMS); Laboratoire d'analyse et d'architecture des systèmes (LAAS); Université Toulouse Capitole (UT Capitole); Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse); Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université Toulouse - Jean Jaurès (UT2J); Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3); Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP); Université de Toulouse (UT)-Université Toulouse Capitole (UT Capitole); Université de Toulouse (UT); Les Hôpitaux Universitaires de Strasbourg (HUS); Nanomédecine Régénérative (NanoRegMed); Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM); Digital Medical Hub, AP-HP; Georgia Institute of Technology Lorraine, France; Maladies neurodéveloppementales et neurovasculaires (NeuroDiderot (UMR_S_1141 / U1141)); Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité); AP-HP - Hôpital Bichat - Claude Bernard Paris; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
    • بيانات النشر:
      HAL CCSD
      MDPI
    • الموضوع:
      2022
    • Collection:
      Université Toulouse 2 - Jean Jaurès: HAL
    • نبذة مختصرة :
      International audience ; (1) Backround: Technological advances should foster gains in physicians’ efficiency. For example, a reduction of the medical decision time can be enabled by faster biological tests. The main objective of this study was to collect responses from an international panel of physicians on their needs for biomarkers and also to convey the improvement in the outcome to be made possible by the potential development of fast diagnostic tests for these biomarkers. (2) Methods: we distributed a questionnaire on the Internet to physicians. (3) Results: 508 physicians participated in this survey. The mean age was 38 years. General practice and emergency medicine were heavily represented, with 95% CIs of 44% (39.78, 48.41) and 32% (27.84, 35.94)), respectively. The two most represented countries were France (95% CI: 74% (70.20, 77.83)) and the USA (95% CI: 11% (8.65, 14.18)). Ninety-eight percentages of the physicians thought that obtaining cited biomarkers more quickly would be beneficial to their practice and to patient’s care. The main biomarkers of interest identified by our panel were troponin (95% CI: 51% (46.24, 54.94)), C-reactive protein (95% CI: 42% (38.03, 46.62)), D-dimer (95% CI: 29% (24.80, 32.68)), and brain natriuretic peptide (95% CI: 13% (10.25, 16.13)). (4) Conclusions: Our study highlights the real technological need for fast biomarker results, which could be provided by biosensors. The relevance of some answers such as troponin is questionable.
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/35055421; hal-03835475; https://hal.science/hal-03835475; https://hal.science/hal-03835475/document; https://hal.science/hal-03835475/file/jpm-12-00106.pdf; PUBMED: 35055421; PUBMEDCENTRAL: PMC8778050
    • الرقم المعرف:
      10.3390/jpm12010106
    • Rights:
      http://creativecommons.org/licenses/by/ ; info:eu-repo/semantics/OpenAccess
    • الرقم المعرف:
      edsbas.AF2FE4E1