Figure S3 from Halloween genes in panarthropods and the evolution of the early moulting pathway in Ecdysozoa

Uncondensed phylogenetic tree of the nuclear hormone receptor genes. The tree is based on a maximum likelihood analysis of 173 sequences from different bilaterian species. Numbers at nodes indicate bootstrap support values >50 % obtained from 1,000 pseudoreplicates. Note that the homologs of ecdysone receptor ( EcR ), beta fushi tarazu transcription factor 1 ( Ftz-F1 ), hormone receptor 3 ( HR3 ), hormone receptor 4 ( HR4 ), ecdysone-inducible genes E75 and E78 , and ultraspiracle/retinoid X receptor ( USP/RXR ) are present in the onychophoran Euperipatoides rowelli (highlighted in brown) and the tardigrades Hypsibius exemplaris and Ramazzottius varieornatus (both highlighted in blue).