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Reproductive health in adolescent girls with special emphasis on menstrual disorders, bone health, sexuality and social factors

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اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • بيانات النشر:
      Institutionen för kvinnors och barns hälsa / Department of Women's and Children's Health
    • الموضوع:
      2009
    • Collection:
      Karolinska Institutet: Publications
    • نبذة مختصرة :
      Menstrual disturbances are common during adolescence, especially within the first 1-3 years after menarche, and are often explained by immaturity of the hypothalamic-pituitary-gonadal axis. However, little is known about the underlying mechanisms, long-term medical consequences and other reproductive health issues in teenagers. The general aim of this thesis was to investigate aspects of reproductive health in adolescent girls and boys visiting a youth clinic. Endocrine mechanisms of menstrual disorders, eating behavior and long-term medical consequences, including bone mass, were specifically evaluated. The aim was also to study sexuality and social factors in adolescent girls in comparison with boys. The mechanisms of menstrual disorders were studied in 203 girls, 117 with secondary amenorrhea and 86 with oligomenorrhea. Hypothalamic amenorrhea dominated in the girls with secondary amenorrhea, whereas hyperandrogenism, i.e. polycystic ovary syndrome (PCOS) was the main mechanism in the oligomenorrheic group. Eating disorders were common (53%); anorectic behavior in the secondary amenorheic group and bulimic type more frequent in the oligomenorrheic group. A follow-up study was performed six years later among 87 of the originally investigated girls; 52 with previous secondary amenorrhea and 35 with previous oligomenorrhea. Menstrual disturbances were still present in 62% of the subjects not using hormonal contraception; 59% of them fulfilled the criteria for PCOS, which was the main mechanism explaining persistent menstrual disorder. Recovery from anorectic eating beahvior was a strong predictor of resumption of regular menstruation. Bone mineral density (BMD) was assessed in the 87 women participating in the follow-up and measured with whole-body dual energy X-ray absorptiometry (DXA). The frequency of osteopenia/osteoporosis was 52%; 3 women had osteoporosis. Those with previous secondary amenorrhea had significantly lower BMD in pelvis and lumbar spine than those with previous oligomenorrhea. Restrictive ...
    • File Description:
      application/pdf
    • ISBN:
      978-91-7409-438-1
      91-7409-438-6
    • Relation:
      I. Wiksten-Almströmer M, Hirschberg AL, Hagenfeldt K (2007). Menstrual disorders and associated factors among adolescent girls visiting a youth clinic. Acta Obstet Gynecol Scand. 86(1): 65-72 ::pmid::17230292; II. Wiksten-Almströmer M, Hirschberg AL, Hagenfeldt K (2008). Prospective follow-up of menstrual disorders in adolescence and prognostic factors. Acta Obstet Gynecol Scand. 87(11): 1162-8 ::pmid::18956264; III. Wikström-Almströmer M, Lindén Hirschberg A, Hagenfeldt K (2009). Reduced bone mineral density in adult women diagnosed with menstrual disorders during adolescence. Acta Obstet Gynecol Scand. 88(5): 543-9 ::pmid::19353333; IV. Wikström-Almströmer M (1970). Gender differences in sexuality and life quality among young people visiting a Swedish youth clinic. Int J Adolesc Med Health. 21(1): 29-39; 20090601wiks; http://hdl.handle.net/10616/38469
    • Rights:
      info:eu-repo/semantics/openAccess
    • الرقم المعرف:
      edsbas.A8AFC37B