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Vaccination against HPV: Theoretical Aspects and Practical Results of Cervical Cancer Prevention ; Вакцинация против ВПЧ: теоретические аспекты и практические результаты профилактики рака шейки матки

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  • معلومة اضافية
    • بيانات النشر:
      «Numicom» LLC
    • الموضوع:
      2020
    • Collection:
      Epidemiology and Vaccine Prevention (E-Journal) / Эпидемиология и Вакцинопрофилактика
    • نبذة مختصرة :
      Relevance. Cervical cancer (CC) continues to be the focus of attention of oncologists all over the world due to the fact that the incidence of it over the past decades has not tended to decrease. The steady increase in morbidity, high mortality rates, and the tendency to «rejuvenate» the disease, the relatively low detection rate of the early stages of the disease due to poor results of cytological screening predetermine the search for new scientifically based approaches to solving cervical cancer problems. A promising direction for the prevention of squamous cell carcinoma and adenocarcinoma associated with human papillomavirus (HPV) is prophylactic vaccination against HPV, the need for which is due to the role of HPV infection in carcinogenesis processes.The aim of this article is to summarize the currently available data on advances in the prevention of precancerous lesions and cervical cancer, primarily through vaccination against HPV infection.Conclusions. The creation of vaccines for the prevention of oncogenic HPV types is a significant achievement in the biomedical research area. The successful development of a group of vaccines, which can confidently be called the vaccines of the 21st century, gives us hope that modern medicine has the potential to reduce population cancer risk and reduce the likelihood of early onset of cervical cancer. Demonstration of the efficacy and feasibility of routine HPV vaccination programs in a number of countries demonstrates encouraging progress in solving cervical cancer problems. Vaccination against HPV will not only ensure epidemiological well-being, but also lead to a decrease in morbidity and mortality from such a terrible complication of human papillomavirus infection – cervical cancer. ; Актуальность. Рак шейки матки (РШМ) продолжает оставаться в центре внимания ведущих зарубежных и отечественных онкологов ввиду того, что заболеваемость им на протяжении последних десятилетий не имеет тенденции к снижению. Неуклонный рост заболеваемости, высокие показатели ...
    • File Description:
      application/pdf
    • Relation:
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    • الرقم المعرف:
      10.31631/2073-3046-2019-18-6-98-108
    • الدخول الالكتروني :
      https://doi.org/10.31631/2073-3046-2019-18-6-98-108
      https://doi.org/10.31631/2073-3046-2019-18-6
      https://www.epidemvac.ru/jour/article/view/872
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      Authors who publish with this journal agree to the following terms:Authors retain copyright and grant to the journal the right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.Authors may enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access). ; Авторы, публикующиеся в данном журнале, соглашаются со следующим:Авторы сохраняют за собой авторские права на работу и предоставляют журналу право первой публикации работы на условиях лицензии Creative Commons Attribution License, которая позволяет другим распространять данную работу с обязательным сохранением ссылок на авторов оригинальной работы и оригинальную публикацию в этом журнале.Авторы сохраняют право заключать отдельные контрактные договорённости, касающиеся не-эксклюзивного распространения версии работы в опубликованном здесь виде (например, размещение ее в институтском хранилище, публикацию в книге), со ссылкой на ее оригинальную публикацию в этом журнале.Авторы имеют право размещать их работу в сети Интернет (например в институтском хранилище или персональном сайте) до и во время процесса рассмотрения ее данным журналом, так как это может привести к продуктивному обсуждению и большему количеству ссылок на данную работу (См. The Effect of Open Access).
    • الرقم المعرف:
      edsbas.A72C37A4