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Comparing the use of midline catheters versus peripherally inserted central catheters for patients requiring peripherally compatible therapies: A pilot randomised controlled trial (the compact trial)

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  • معلومة اضافية
    • بيانات النشر:
      Elsevier BV
    • الموضوع:
      2023
    • Collection:
      Griffith University: Griffith Research Online
    • نبذة مختصرة :
      Background: Midline catheter (MC) use has increased in acute-care settings, particularly for patients with difficult venous access or requiring peripherally compatible intravenous therapy for up-to 14 days. Our aim was to assess feasibility and generate clinical data comparing MCs with Peripherally Inserted Central Catheters (PICCs). Methods: A two-arm parallel group pilot randomised controlled trial (RCT), comparing MCs with PICCs, was conducted in a large tertiary hospital in Queensland between September 2020 and January 2021. The primary outcome was study feasibility, measured against rates of eligibility (>75%), consent (>90%), attrition (<5%); protocol adherence (>90%) and missing data (<5%). The primary clinical outcome was all-cause device failure. Results: In total, 25 patients were recruited. The median patient age was 59–62 years; most patients were overweight/obese, with ≥2 co-morbidities. Primary outcomes: The eligibility and protocol adherence criteria were not met; of 159 screened patients, only 25 (16%) were eligible, and three patients did not receive their allocated intervention post-randomisation (88% adherence). All-cause failure occurred in two patients allocated to MC (20%) and one PICC (8.3%). Conclusions: Our study found that a fully powered RCT testing MCs compared with PICCs is not currently feasible in our setting. We recommend a robust process evaluation before the introduction of MCs into clinical practice. ; No Full Text
    • ISSN:
      2468-0451
    • Relation:
      Infection, Disease & Health; Marsh, N; Larsen, EN; O'Brien, C; Groom, P; Kleidon, TM; Alexandrou, E; Young, E; McCarthy, K; Rickard, CM, Comparing the use of midline catheters versus peripherally inserted central catheters for patients requiring peripherally compatible therapies: A pilot randomised controlled trial (the compact trial), Infection, Disease & Health, 2023; http://hdl.handle.net/10072/425000
    • الرقم المعرف:
      10.1016/j.idh.2023.03.007
    • الدخول الالكتروني :
      http://hdl.handle.net/10072/425000
      https://doi.org/10.1016/j.idh.2023.03.007
    • Rights:
      open access
    • الرقم المعرف:
      edsbas.A2A90A68