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Heatmap of aminaocid that interact with cdALK + /iALK and cdALK + /FDA-approved drugs.

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اقرأ أكثر حفظ في قائمتي

المؤلفون: Juan Enrique Faya Castillo; Richard Junior Zapata Dongo; Paolo Alberto Wong Chero; Stefany Fiorella Infante Varillas
الموضوع:
Biophysics; Biochemistry; Medicine; Cell Biology; Molecular Biology; Pharmacology; Biotechnology; Cancer; Biological Sciences not elsewhere classified; Chemical Sciences not elsewhere classified; sup >+; lung cancer associated; div >< p; different atomistic characteristics; deregulated catalytic domain; best interaction energies; based virtual screening; performed molecular docking; identified pharmacophores sites; different alk inhibitors; alk inhibitory characteristics; special literature proposed; proposed atomistic positions; used homology modelling; study proposes fda; identify potential ialks; aberrant protein kinase; approved drugs library; molecular dynamics; four pharmacophores
نوع التسجيلة:
dataset
اللغة:
unknown

معلومة اضافية
- الموضوع:
  2024
- Collection:
  Smithsonian Institution: Figshare
- نبذة مختصرة :
  A) shows the aminoacids that have hydrogen bond interaction with the drugs under study, in addition to the rate throughout all the dynamics. B) shows the amino acids that have hydrophobic bond interactions with the drugs under study, in addition to the rate throughout all the dynamics. The yellow squares are amino acid that are not present in the interactions with iALK or FDA-approved drugs. (ZIP)
- Relation:
  https://figshare.com/articles/dataset/Heatmap_of_aminaocid_that_interact_with_cdALK_sup_sup_iALK_and_cdALK_sup_sup_FDA-approved_drugs_/25153773
- الرقم المعرف:
  10.1371/journal.pone.0295966.s006
- الدخول الالكتروني :
  https://doi.org/10.1371/journal.pone.0295966.s006
- Rights:
  CC BY 4.0
- الرقم المعرف:
  edsbas.98439CBC

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