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COVID-19 infection in patients on long-term home parenteral nutrition for chronic intestinal failure

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اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • Contributors:
      Alma Mater Studiorum Università di Bologna = University of Bologna (UNIBO); Cleveland Clinic; Centre of Postgraduate Medical Education; University of Manchester Manchester; Catholic University of Leuven = Katholieke Universiteit Leuven (KU Leuven); Tel Aviv University (TAU); Hospices Civils de Lyon (HCL); Poznan University of Life Sciences (Uniwersytet Przyrodniczy w Poznaniu) (PULS); Città della Salute e della Scienza di Torino (A.O.U); Aalborg University Denmark (AAU); University Hospital of Wales (UHW); University of Lódź = Uniwersytet Łódzki; Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille); Institute for Translational Research in Inflammation - U 1286 (INFINITE); Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille); Centre Hospitalier Universitaire de Nice (CHU Nice); Nottingham University Hospitals NHS Trust (NUH); CHU Bordeaux; Mayo Clinic and Mayo College of Medicine; Medical University of Lublin; Medical University of Gdańsk; Hospital Universitario Fundacion Favaloro; University Hospital Coventry; Sahlgrenska Academy at University of Gothenburg Göteborg; University of Naples Federico II = Università degli studi di Napoli Federico II; Hôpital Erasme Bruxelles; Clinique Saint-Yves Rennes; Centre Hospitalier Universitaire de Rennes CHU Rennes = Rennes University Hospital Ponchaillou; Nutrition, Métabolismes et Cancer (NuMeCan); Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE); Universidad de Málaga Málaga = University of Málaga Málaga; Mahidol University Bangkok; University of Sakarya; Hôpital Beaujon AP-HP; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP); The project of the ESPEN database for Chronic Intestinal Failure was promoted by the ESPEN Executive Committee in 2013, was approved by the ESPEN Council and was supported by an ESPEN grant.
    • بيانات النشر:
      HAL CCSD
      ESPEN/Elsevier
    • الموضوع:
      2023
    • Collection:
      LillOA (HAL Lille Open Archive, Université de Lille)
    • نبذة مختصرة :
      International audience ; Background and aims - To investigate the incidence and the severity of COVID-19 infection in patients enrolled in the database for home parenteral nutrition (HPN) for chronic intestinal failure (CIF) of the European Society for Clinical Nutrition and Metabolism (ESPEN). Methods - Period of observation: March 1st, 2020 March 1st, 2021. Inclusion criteria - patients included in the database since 2015 and still receiving HPN on March 1st, 2020 as well as new patients included in the database during the period of observation. Data related to the previous 12 months and recorded on March 1st 2021: 1) occurrence of COVID-19 infection since the beginning of the pandemic (yes, no, unknown); 2) infection severity (asymptomatic; mild, no-hospitalization; moderate, hospitalization no-ICU; severe, hospitalization in ICU); 3) vaccinated against COVID-19 (yes, no, unknown); 4) patient outcome on March 1st 2021: still on HPN, weaned off HPN, deceased, lost to follow up. Results - Sixty-eight centres from 23 countries included 4680 patients. Data on COVID-19 were available for 55.1% of patients. The cumulative incidence of infection was 9.6% in the total group and ranged from 0% to 21.9% in the cohorts of individual countries. Infection severity was reported as: asymptomatic 26.7%, mild 32.0%, moderate 36.0%, severe 5.3%. Vaccination status was unknown in 62.0% of patients, non-vaccinated 25.2%, vaccinated 12.8%. Patient outcome was reported as: still on HPN 78.6%, weaned off HPN 10.6%, deceased 9.7%, lost to follow up 1.1%. A higher incidence of infection (p = 0.04), greater severity of infection (p < 0.001) and a lower vaccination percentage (p = 0.01) were observed in deceased patients. In COVID-19 infected patients, deaths due to infection accounted for 42.8% of total deaths. Conclusions - In patients on HPN for CIF, the incidence of COVID-19 infection differed greatly among countries. Although the majority of cases were reported to be asymptomatic or have mild symptoms only, COVID-19 was ...
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/37202049; hal-04089872; https://univ-rennes.hal.science/hal-04089872; https://univ-rennes.hal.science/hal-04089872/document; https://univ-rennes.hal.science/hal-04089872/file/Pironi%20et%20al.%20-%202023%20-%20Covid-19%20Infection%20In%20Patients%20On%20Long-Term%20Home%20P.pdf; PUBMED: 37202049; PUBMEDCENTRAL: PMC10032093; WOS: 000979839600001
    • الرقم المعرف:
      10.1016/j.clnesp.2023.03.008
    • Rights:
      http://creativecommons.org/licenses/by-nc/ ; info:eu-repo/semantics/OpenAccess
    • الرقم المعرف:
      edsbas.98110A0D