Contributors: Munoz-Hernando, Leticia Univ Hosp 12 Octubre, Dept Obstet & Gynaecol, Colposcopy & Cerv Pathol Unit, Madrid 28041, Spain; Oliver-Perez, Reyes Univ Hosp 12 Octubre, Dept Obstet & Gynaecol, Colposcopy & Cerv Pathol Unit, Madrid 28041, Spain; Bravo-Violeta, Victoria Univ Hosp 12 Octubre, Dept Obstet & Gynaecol, Colposcopy & Cerv Pathol Unit, Madrid 28041, Spain; Olloqui, Alejandro Univ Hosp 12 Octubre, Dept Obstet & Gynaecol, Colposcopy & Cerv Pathol Unit, Madrid 28041, Spain; Parte-Izquierdo, Belen Univ Hosp 12 Octubre, Dept Obstet & Gynaecol, Colposcopy & Cerv Pathol Unit, Madrid 28041, Spain; Almansa-Gonzalez, Cristina Univ Hosp 12 Octubre, Dept Obstet & Gynaecol, Colposcopy & Cerv Pathol Unit, Madrid 28041, Spain; Bermejo-Martinez, Rocio Univ Hosp 12 Octubre, Dept Obstet & Gynaecol, Colposcopy & Cerv Pathol Unit, Madrid 28041, Spain; Bolivar-De Miguel, Ana Belen Univ Hosp 12 Octubre, Dept Obstet & Gynaecol, Colposcopy & Cerv Pathol Unit, Madrid 28041, Spain; Diez, Alvaro Univ Hosp 12 Octubre, Dept Obstet & Gynaecol, Colposcopy & Cerv Pathol Unit, Madrid 28041, Spain; Seoane-Ruiz, Jose Miguel Univ Hosp 12 Octubre, Dept Obstet & Gynaecol, Colposcopy & Cerv Pathol Unit, Madrid 28041, Spain; Oliver-Perez, Reyes Univ Complutense Madrid, Inst Invest Sanitaria Hosp 12 Octubre, Imas12, Madrid 28041, Spain; Bravo-Violeta, Victoria Univ Complutense Madrid, Inst Invest Sanitaria Hosp 12 Octubre, Imas12, Madrid 28041, Spain; Olloqui, Alejandro Univ Complutense Madrid, Inst Invest Sanitaria Hosp 12 Octubre, Imas12, Madrid 28041, Spain; Tejerizo-Garcia, Alvaro Univ Complutense Madrid, Inst Invest Sanitaria Hosp 12 Octubre, Imas12, Madrid 28041, Spain; Oliver-Perez, Reyes Univ Hosp 12 Octubre, Dept Obstet & Gynaecol, Gynaecol Oncol Unit, Avda Cordoba S-N, Madrid 28041, Spain; Tejerizo-Garcia, Alvaro Univ Hosp 12 Octubre, Dept Obstet & Gynaecol, Gynaecol Oncol Unit, Avda Cordoba S-N, Madrid 28041, Spain; Parrilla-Rubio, Lucia Univ Hosp 12 Octubre, Dept Pathol, Avda Andalucia S-N, Madrid 28041, Spain
نبذة مختصرة : Background: Women living with human immunodeficiency virus (HIV), WLWHs, are at high risk of developing anal cancer associated with high-risk human papilloma virus infection (HR-HPV). We analyzed the prevalence of anal HR-HPV infection and abnormal anal cytology in a cohort of WLWHs and assessed the risk factors for anal HR-HPV infection. Methods: We present a single-center, observational cross-sectional study. WLWHs who underwent anal cytology and anal human papilloma virus (HPV) testing were selected. High-resolution anoscopy was performed in cases of abnormal anal cytology. All suspicious lesions were biopsied. A univariate and multivariate logistic regression model was used to analyze risk factors for abnormal anal screening. The results are presented as odds ratios (ORs) and 95% confidence intervals (CIs). Results: In total, 400 WLWHs were studied. Of them, 334 met the eligibility criteria and were enrolled in the study. Abnormal anal cytology was detected in 39.5% of patients, and anal HR-HPV in 40.1%, with HPV 16 in 33 (26.6%) of them. Concomitant HR-HPV cervical infection was the only independent risk factor for HR-HPV anal infection (OR 1.67 95% CI, p
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