Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Bayesian inference of a non-local proliferation model

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
  • معلومة اضافية
    • الموضوع:
      2021
    • Collection:
      ArXiv.org (Cornell University Library)
    • نبذة مختصرة :
      From a systems biology perspective the majority of cancer models, although interesting and providing a qualitative explanation of some problems, have a major disadvantage in that they usually miss a genuine connection with experimental data. Having this in mind, in this paper, we aim at contributing to the improvement of many cancer models which contain a proliferation term. To this end, we propose a new non-local model of cell proliferation. We select data which are suitable to perform a Bayesian inference for unknown parameters and we provide a discussion on the range of applicability of the model. Furthermore, we provide proof of the stability of a posteriori distributions in total variation norm which exploits the theory of spaces of measures equipped with the weighted flat norm. In a companion paper, we provide a detailed proof of the well-posedness of the problem and we investigate the convergence of the EBT algorithm applied to solve the equation.
    • Relation:
      http://arxiv.org/abs/2106.05955
    • الرقم المعرف:
      10.1098/rsos.211279
    • الرقم المعرف:
      edsbas.96FDE7F4